Bousfiha, A;
Jeddane, L;
Picard, C;
Ailal, F;
Gaspar, HB;
Al-Herz, W;
Chatila, T;
... Sullivan, KE; + view all
(2018)
The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies.
Journal of Clinical Immunology
, 38
(1)
pp. 129-143.
10.1007/s10875-017-0465-8.
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Abstract
Since the 1990s, the International Union of Immunological Societies (IUIS) PID expert committee (EC), now called Inborn Errors of Immunity Committee, has published every other year a classification of the inborn errors of immunity. This complete catalog serves as a reference for immunologists and researchers worldwide. However, it was unadapted for clinicians at the bedside. For those, the IUIS PID EC is now publishing a phenotypical classification since 2013, which proved to be more user-friendly. There are now 320 single-gene inborn errors of immunity underlying phenotypes as diverse as infection, malignancy, allergy, auto-immunity, and auto-inflammation. We herein propose the revised 2017 phenotypic classification, based on the accompanying 2017 IUIS Inborn Errors of Immunity Committee classification.
| Type: | Article |
|---|---|
| Title: | The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/s10875-017-0465-8 |
| Publisher version: | http://doi.org/10.1007/s10875-017-0465-8 |
| Language: | English |
| Additional information: | Copyright information © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| Keywords: | Primary immunodeficiencies, Classification Phenotypic, IUIS Inborn errors of immunity |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL GOS Institute of Child Health |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10041359 |
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