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Number of items: 9.

Article

Cohen, SIA; Cukalevski, R; Michaels, TCT; Saric, A; Tornquist, M; Vendruscolo, M; Dobson, CM; ... Linse, S; + view all (2018) Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-beta peptide. Nature Chemistry , 10 (5) pp. 523-531. 10.1038/s41557-018-0023-x. Green open access
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Dear, AJ; Meisl, G; Šarić, A; Michaels, TCT; Kjaergaard, M; Linse, S; Knowles, TPJ; (2020) Identification of on- and off-pathway oligomers in amyloid fibril formation. Chemical Science 10.1039/c9sc06501f. (In press). Green open access
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Kundel, F; Hong, L; Falcon, B; McEwan, WA; Michaels, TCT; Meisl, G; Esteras, N; ... Klenerman, D; + view all (2018) Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading. ACS Chemical Neuroscience 10.1021/acschemneuro.8b00094. (In press). Green open access
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Michaels, TCT; Dear, AJ; Cohen, S; Vendruscolo, M; Knowles, TPJ; (2022) Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers. The Journal of Chemical Physics 10.1063/5.0077609. (In press). Green open access
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Michaels, TCT; Saric, A; Meisl, G; Heller, GT; Curk, S; Arosio, P; Linse, S; ... Knowles, TPJ; + view all (2020) Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors. Proceedings of the National Academy of Sciences of the United States of America , 117 (39) pp. 24251-24257. 10.1073/pnas.2006684117. Green open access
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Michaels, TCT; Liu, LX; Curk, S; Bolhuis, PG; Šarić, A; Knowles, TPJ; (2018) Reaction rate theory for supramolecular kinetics: application to protein aggregation. Molecular Physics , 116 (21-22) pp. 3055-3065. 10.1080/00268976.2018.1474280. Green open access
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Michaels, TCT; Šarić, A; Curk, S; Bernfur, K; Arosio, P; Meisl, G; Dear, AJ; ... Knowles, TPJ; + view all (2020) Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide. Nature Chemistry , 12 pp. 445-451. 10.1038/s41557-020-0452-1. Green open access
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Saric, A; Buell, AK; Meisl, G; Michaels, TCT; Dobson, CM; Linse, S; Knowles, TPJ; (2016) Physical determinants of the self-replication of protein fibrils. Nature Physics , 12 (9) pp. 874-880. 10.1038/NPHYS3828. Green open access
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Šarić, A; Michaels, TCT; Zaccone, A; Knowles, TPJ; Frenkel, D; (2016) Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation. The Journal of Chemical Physics , 145 (21) , Article 211926. 10.1063/1.4965040. Green open access
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