Browse by UCL people
Group by: Type | Date
Number of items: 25.
Article
Anderson, Nathaniel D;
Birch, Jack;
Accogli, Theo;
Criado, Ignacio;
Khabirova, Eleonora;
Parks, Conor;
Wood, Yvette;
... Ghorashian, Sara; + view all
(2023)
Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia.
Nature Medicine
10.1038/s41591-023-02415-3.
(In press).
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Biasco, L;
Izotova, N;
Rivat, C;
Ghorashian, S;
Richardson, R;
Guvenel, A;
Hough, R;
... Amrolia, PJ; + view all
(2021)
Clonal expansion of T memory stem cells determines early anti-leukemic responses and long-term CAR T cell persistence in patients.
Nature Cancer
, 2
pp. 629-64.
10.1038/s43018-021-00207-7.
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Clesham, K;
Rao, V;
Bartram, J;
Ancliff, P;
Ghorashian, S;
O'Connor, D;
Pavasovic, V;
... Vora, A; + view all
(2020)
Blinatumomab for infant acute lymphoblastic leukemia.
Blood
, 135
(17)
pp. 1501-1504.
10.1182/blood.2019004008.
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Cordoba, S;
Onuoha, S;
Thomas, S;
Pignataro, DS;
Hough, R;
Ghorashian, S;
Vora, A;
... Amrolia, PJ; + view all
(2021)
CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial.
Nature Medicine
, 27
pp. 1797-1805.
10.1038/s41591-021-01497-1.
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Gabelli, Maria;
Oporto-Espuelas, Macarena;
Bonney, Denise Kathleen;
Burridge, Saskia;
Farish, Susan;
Mullanfiroze, Khushnuma;
Lazareva, Arina;
... Ghorashian, Sara; + view all
(2024)
Maintenance therapy for early loss of B-cell aplasia after CD19 CAR T-cell therapy.
Blood Advances
, 8
(8)
pp. 1959-1963.
10.1182/bloodadvances.2023011168.
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Ghorashian, Sara;
Lucchini, Giovanna;
Richardson, Rachel;
Nguyen, Kyvi;
Terris, Craig;
Guvenel, Aleks;
Oporto Espuelas, Macarena;
... Amrolia, Persis J; + view all
(2024)
CD19/CD22 targeting with co-transduced CAR T-cells to prevent antigen negative relapse after CAR T-cell therapy of B-ALL.
Blood
, 143
(2)
pp. 118-123.
10.1182/blood.2023020621.
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Ghorashian, S;
Amrolia, P;
Veys, P;
(2018)
Open access? Widening access to chimeric antigen receptor (CAR) therapy for ALL.
Experimental Hematology
, 66
pp. 5-16.
10.1016/j.exphem.2018.07.002.
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Ghorashian, S;
Kramer, AM;
Onuoha, S;
Wright, G;
Bartram, J;
Richardson, R;
Albon, SJ;
... Amrolia, PJ; + view all
(2019)
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.
Nature Medicine
, 25
pp. 1408-1414.
10.1038/s41591-019-0549-5.
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Ghorashian, S;
Veliça, P;
Chua, I;
McNicol, AM;
Carpenter, B;
Holler, A;
Nicholson, E;
... Stauss, HJ; + view all
(2015)
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Journal of Immunology
, 194
(3)
1080 - 1089.
10.4049/jimmunol.1401703.
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Gkazi, Soragia Athina;
Gravett, Emma;
Bautista, Carla;
Bartram, Jack;
Ghorashian, Sara;
Adams, Stuart Paul;
(2022)
Clinically Applicable Assessment of Tisagenlecleucel CAR T Cell Treatment by Digital Droplet PCR for Copy Number Variant Assessment.
International Journal of Molecular Sciences
, 23
(14)
, Article 7573. 10.3390/ijms23147573.
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Green, K;
Pavasovic, V;
Ghorashian, S;
Ancliff, P;
Bartram, J;
Rao, A;
Samarasinghe, S;
... O'Connor, D; + view all
(2021)
Clinical Utility of Radiologic Disease Reassessment in the Management of Pediatric B-Cell Non-Hodgkin Lymphoma.
Journal of Pediatric Hematology/Oncology
, 43
(3)
e380-e384.
10.1097/MPH.0000000000001781.
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Holler, A;
Zech, M;
Ghorashian, S;
Pike, R;
Hotblack, A;
Velica, P;
Xue, S-A;
... Stauss, HJ; + view all
(2016)
Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy.
Haematologica
, 101
(4)
pp. 482-490.
10.3324/haematol.2015.132712.
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Khan, AB;
Carpenter, B;
Sousa, PSE;
Pospori, C;
Khorshed, R;
Griffin, J;
Veliça, P;
... Chakraverty, R; + view all
(2018)
Redirection to the bone marrow improves T cell persistence and antitumor functions.
The Journal of Clinical Investigation
, 128
(5)
pp. 2010-2024.
10.1172/JCI97454.
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Leong, S;
Inglott, S;
Papaleonidopoulou, F;
Orfinada, K;
Ancliff, P;
Bartram, J;
Carpenter, B;
... O'Connor, D; + view all
(2020)
CD1a is rarely expressed in pediatric or adult relapsed/refractory T-ALL: implications for immunotherapy.
Blood Advances
, 4
(19)
pp. 4665-4668.
10.1182/bloodadvances.2020002502.
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Mishra, Avijeet Kumar;
Burridge, Saskia;
Espuelas, Macarena Oporto;
O'Reilly, Maeve;
Cummins, Michelle;
Nicholson, Emma;
Wheldon, Sophie;
... Ghorashian, Sara; + view all
(2024)
Practice guideline: Preparation for CAR T-cell therapy in children and young adults with B-acute lymphoblastic leukaemia.
British Journal of Haematology
10.1111/bjh.19381.
(In press).
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Orf, K;
Rogosic, S;
Dexter, D;
Ancliff, P;
Badle, S;
Brierley, J;
Cheng, D;
... Bartram, J; + view all
(2020)
Remdesivir during induction chemotherapy for newly diagnosed paediatric acute lymphoblastic leukaemia with concomitant SARS-CoV-2 infection.
British Journal of Haematology
, 190
(5)
E274-E276.
10.1111/bjh.17014.
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Ottaviano, G;
Baird, S;
Bonney, D;
Connor, P;
Cummins, M;
Evans, P;
Gibson, B;
... Vora, A; + view all
(2021)
The role of immunotherapy in relapse/refractory precursor-B acute lymphoblastic leukaemia: real-life UK/Ireland experience in children and young adults.
British Journal of Haematology
, 192
(2)
e42-e44.
10.1111/bjh.17198.
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Peggs, Karl S;
Albon, Sarah J;
Oporto Espuelas, Macarena;
Irving, Catherine;
Richardson, Rachel;
Casanovas-Company, Joan;
Wallace, Rebecca;
... Amrolia, Persis J; + view all
(2022)
Immunotherapy with CD25/CD71-allodepleted T cells to improve T-cell reconstitution after matched unrelated donor hematopoietic stem cell transplant: a randomized trial.
Cytotherapy
10.1016/j.jcyt.2022.08.010.
(In press).
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Pozzilli, Valeria;
Thambiliyagodage, Manori Prasadani;
Mankad, Kshitij;
Worth, Austen;
Brogan, Paul;
Ghorashian, Sara;
Bamford, Alasdair;
... Hacohen, Yael; + view all
(2025)
CSF IL-6 in children with neuroinflammatory conditions.
European Journal of Paediatric Neurology
, 58
pp. 42-49.
10.1016/j.ejpn.2025.07.013.
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Qasim, W;
Zhan, H;
Samarasinghe, S;
Adams, S;
Amrolia, P;
Stafford, S;
Butler, K;
... Veys, P; + view all
(2017)
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.
Science Translational Medicine
, 9
(374)
, Article eaaj2013. 10.1126/scitranslmed.aaj2013.
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Rogosic, S;
Ghorashian, S;
(2020)
CAR-T cell therapy in paediatric acute lymphoblastic leukaemia - past, present and future.
British Journal of Haematology
, 191
(4)
pp. 617-626.
10.1111/bjh.17153.
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Rossig, C;
Pule, M;
Altvater, B;
Saiagh, S;
Wright, G;
Ghorashian, S;
Clifton-Hadley, L;
... Amrolia, PJ; + view all
(2017)
Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia.
Leukemia
, 31
pp. 1087-1095.
10.1038/leu.2017.39.
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Vormittag, P;
Gunn, R;
Ghorashian, S;
Veraitch, FS;
(2018)
A guide to manufacturing CAR T cell therapies.
Current Opinion in Biotechnology
, 53
pp. 164-181.
10.1016/j.copbio.2018.01.025.
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Thesis
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Ghorashian, S;
(2014)
Overcoming T cell tolerance to tumour antigens: an evaluation of the role of helper responses.
Doctoral thesis , UCL (University College London).
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Kramer, AM;
(2017)
Delineating the impact of binding-domain affinity and kinetic properties on Chimeric Antigen Receptor T-cell function.
Doctoral thesis , UCL (University College London).
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