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Number of items: 21.
Article
Chetty, S;
Armstrong, T;
Sharma Kharkwal, S;
Drewe, WC;
De Matteis, CI;
Evangelopoulos, D;
Bhakta, S;
(2021)
New InhA Inhibitors Based on Expanded Triclosan and Di-Triclosan Analogues to Develop a New Treatment for Tuberculosis.
Pharmaceuticals
, 14
(4)
, Article 361. 10.3390/ph14040361.
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Danquah, CA;
Kakagianni, E;
Khondkar, P;
Maitra, A;
Rahman, M;
Evangelopoulos, D;
McHugh, TD;
... Gibbons, S; + view all
(2018)
Analogues of Disulfides from Allium stipitatum Demonstrate Potent Anti-tubercular Activities through Drug Efflux Pump and Biofilm Inhibition.
Scientific Reports
, 8
, Article 1150. 10.1038/s41598-017-18948-w.
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Ferguson, Lindsay;
Madieh, Nasrin Shokrzadeh;
Vaideanu, Alexandra;
Schatzlein, Andreas;
Festa, Joseph;
Singh, Harprit;
Wells, Geoff;
... Brucoli, Federico; + view all
(2022)
C2-linked alkynyl poly-ethylene glycol(PEG) adenosine conjugates as water-soluble adenosine receptor agonists.
Chemical Biology & Drug Design
10.1111/cbdd.14128.
(In press).
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Ferguson, L;
Bhakta, S;
Fox, KR;
Wells, G;
Brucoli, F;
(2020)
Synthesis and Biological Evaluation of a Novel C8-Pyrrolobenzodiazepine (PBD) Adenosine Conjugate. A Study on the Role of the PBD Ring in the Biological Activity of PBD-Conjugates.
Molecules
, 25
(5)
, Article 1243. 10.3390/molecules25051243.
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Ferguson, L;
Wells, G;
Bhakta, S;
Johnson, J;
Guzman, J;
Parish, T;
Prentice, RA;
(2019)
Integrated target-based and phenotypic screening approaches for the identification of anti-tubercular agents that bind to the mycobacterial adenylating enzyme MbtA.
ChemMedChem
, 14
(19)
pp. 1735-1741.
10.1002/cmdc.201900217.
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Guzman, JD;
Pesnot, T;
Barrera, DA;
Davies, HM;
McMahon, E;
Evangelopoulos, D;
Mortazavi, PN;
... Bhakta, S; + view all
(2015)
Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase.
J Antimicrob Chemother
, 70
(6)
pp. 1691-1703.
10.1093/jac/dkv010.
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Kerai, LV;
Hilton, S;
Maugueret, M;
Kazi, BB;
Faull, J;
Bhakta, S;
Murdan, S;
(2016)
UV-curable gels as topical nail medicines:In vivo residence, anti-fungal efficacy and influence of gel components on their properties.
International Journal of Pharmaceutics
, 514
(1)
pp. 244-254.
10.1016/j.ijpharm.2016.08.025.
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Maitra, A;
Evangelopoulos, D;
Chrzastek, A;
Martin, LT;
Hanrath, A;
Chapman, E;
Hailes, HC;
... Bhakta, S; + view all
(2020)
Carprofen elicits pleiotropic mechanisms of bactericidal action with the potential to reverse antimicrobial drug resistance in tuberculosis.
Journal of Antimicrobial Chemotherapy
, Article dkaa307. 10.1093/jac/dkaa307.
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Maitra, A;
Munshi, T;
Healy, J;
Martin, LT;
Vollmer, W;
Keep, NH;
Bhakta, S;
(2019)
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen.
FEMS Microbiology Reviews
, 43
(5)
pp. 548-575.
10.1093/femsre/fuz016.
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Maitra, A;
Nukala, S;
Dickman, R;
Martin, LT;
Munshi, T;
Gupta, A;
Shepherd, AJ;
... Bhakta, S; + view all
(2021)
Characterization of the MurT/GatD complex in Mycobacterium tuberculosis towards validating a novel anti-tubercular drug target.
JAC-Antimicrobial Resistance
, 3
(1)
10.1093/jacamr/dlab028.
(In press).
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Martin, Liam T;
Daniel, Chris;
Guldberg-Allen, Marcus;
Navaratnarajah, Anushandan;
Anselmi, Silvia;
Burova, Tina-Maria D;
Willcocks, Sam;
... Bhakta, Sanjib; + view all
(2025)
Development of Carprofen analogues with activity against Mycobacterium tuberculosis.
Bioorganic & Medicinal Chemistry
, 127
, Article 118226. 10.1016/j.bmc.2025.118226.
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Munshi, T;
Gupta, A;
Evangelopoulos, D;
Guzman, JD;
Gibbons, S;
Keep, NH;
Bhakta, S;
(2013)
Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis.
PLoS One
, 8
(3)
, Article e60143. 10.1371/journal.pone.0060143.
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Osman, K;
Evangelopoulos, D;
Basavannacharya, C;
Gupta, A;
McHugh, TD;
Bhakta, S;
Gibbons, S;
(2012)
An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis.
International Journal of Antimicrobial Agents
, 39
(2)
124 - 129.
10.1016/j.ijantimicag.2011.09.018.
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Quay, DHX;
Cole, AR;
Cryar, A;
Thalassinos, K;
Williams, MA;
Bhakta, S;
Keep, NH;
(2015)
Structure of the stationary phase survival protein YuiC from B.subtilis.
BMC Structural Biology
, 15
, Article 12. 10.1186/s12900-015-0039-z.
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Rizi, K;
Xu, K;
Begum, T;
Faull, J;
Bhakta, S;
Murdan, S;
(2022)
A drug-in-adhesive anti-onychomycotic nail patch: Influence of drug and adhesive nature on drug release, ungual permeation, in vivo residence in human and anti-fungal efficacy.
International Journal of Pharmaceutics
, 614
, Article 121437. 10.1016/j.ijpharm.2021.121437.
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Rizi, K;
Murdan, S;
Danquah, CA;
Faull, J;
Bhakta, S;
(2015)
Development of a rapid, reliable and quantitative method: "SPOTi" for testing antifungal efficacy.
Journal of Microbiological Methods
, 117
pp. 36-40.
10.1016/j.mimet.2015.07.005.
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Ryan, A;
Polycarpou, E;
Lack, NA;
Evangelopoulos, D;
Sieg, C;
Halman, A;
Bhakta, S;
... Sim, E; + view all
(2017)
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.
British Journal of Pharmacology
, 174
(14)
pp. 2209-2224.
10.1111/bph.13810.
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Shyam, M;
Verma, H;
Bhattacharje, G;
Mukherjee, P;
Singh, S;
Kamilya, S;
Jalani, P;
... Jayaprakash, V; + view all
(2022)
Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition.
Journal of Medicinal Chemistry
, 65
(1)
pp. 234-256.
10.1021/acs.jmedchem.1c01349.
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Teo, SP;
Bhakta, S;
Stapleton, P;
Gibbons, S;
(2020)
Bioactive Compounds from the Bornean Endemic Plant Goniothalamus longistipetes.
Antibiotics
, 9
(12)
, Article 913. 10.3390/antibiotics9120913.
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Touitou, M;
Manetti, F;
Ribeiro, CM;
Pavan, FR;
Scalacci, N;
Zrebna, K;
Begum, N;
... Castagnolo, D; + view all
(2020)
Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria.
ACS Medicinal Chemistry Letters
, 11
(5)
pp. 638-644.
10.1021/acsmedchemlett.9b00515.
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Xia, DQH;
Qureshi, A;
Bhakta, S;
Keep, NH;
(2018)
Mutation studies of the gene encoding YuiC, a stationary phase survival protein in Bacillus subtilis.
Malaysian Journal of Microbiology
, 14
(6)
pp. 444-451.
10.21161/mjm.1461801.
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