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Number of items: 8.

Article

Chakrabarti, AM; Henser-Brownhill, T; Monserrat, J; Poetsch, AR; Luscombe, NM; Scaffidi, P; (2018) Target-Specific Precision of CRISPR-Mediated Genome Editing. Molecular Cell 10.1016/j.molcel.2018.11.031. (In press). Green open access
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Henser-Brownhill, T; Monserrat, J; Scaffidi, P; (2017) Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to in vivo assays. Epigenetics , 12 (12) pp. 1065-1075. 10.1080/15592294.2017.1395121. Green open access
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Morales Torres, C; Wu, MY; Hobor, S; Wainwright, EN; Martin, MJ; Patel, H; Grey, W; ... Scaffidi, P; + view all (2020) Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis. Nature Communications , 11 (1) , Article 1792. 10.1038/s41467-020-15615-z. Green open access
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Mortimer, T; Wainwright, EN; Patel, H; Siow, BM; Jaunmuktane, Z; Brandner, S; Scaffidi, P; (2019) Redistribution of EZH2 promotes malignant phenotypes by rewiring developmental programmes. EMBO Rep , Article e48155. 10.15252/embr.201948155. (In press). Green open access
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Mourikis, TP; Benedetti, L; Foxall, E; Temelkovski, D; Nulsen, J; Perner, J; Cereda, M; ... Ciccarelli, FD; + view all (2019) Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma. Nature Communications , 10 (1) , Article 3101. 10.1038/s41467-019-10898-3. Green open access
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Pal, Debosree; Patel, Manthan; Boulet, Fanny; Sundarraj, Jayakumar; Grant, Olivia A; Branco, Miguel R; Basu, Srinjan; ... Pradeepa, Madapura M; + view all (2023) H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function. Nature Structural & Molecular Biology , 30 pp. 935-947. 10.1038/s41594-023-01016-5. Green open access
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Torres, CM; Biran, A; Burney, MJ; Patel, H; Henser-Brownhill, T; Cohen, A-HS; Li, Y; ... Scaffidi, P; + view all (2016) The linker histone H1.0 generates epigenetic and functional intratumor heterogeneity. Science , 353 (6307) , Article aaf1644. 10.1126/science.aaf1644. Green open access
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Wainwright, EN; Scaffidi, P; (2017) Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity. Trends in cancer , 3 (5) pp. 372-386. 10.1016/j.trecan.2017.04.004. Green open access
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