Browse by UCL people
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Number of items: 14.
Article
Anoar, S;
Woodling, NS;
Niccoli, T;
(2021)
Mitochondria Dysfunction in Frontotemporal Dementia/Amyotrophic Lateral Sclerosis: Lessons From Drosophila Models.
Frontiers in Neuroscience
, 15
, Article 786076. 10.3389/fnins.2021.786076.
|
Bjedov, I;
Cochemé, HM;
Foley, A;
Wieser, D;
Woodling, NS;
Castillo-Quan, JI;
Norvaisas, P;
... Partridge, L; + view all
(2020)
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
PLOS Genetics
, 16
(11)
, Article e1009083. 10.1371/journal.pgen.1009083.
|
Bolukbasi, E;
Woodling, NS;
Ivanov, DK;
Adcott, J;
Foley, A;
Rajasingam, A;
Gittings, LM;
... Partridge, L; + view all
(2021)
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system.
Proceedings of the National Academy of Sciences
, 118
(8)
, Article e2011491118. 10.1073/pnas.2011491118.
|
Gray, SC;
Kinghorn, KJ;
Woodling, NS;
(2020)
Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis.
Neural Regeneration Research
, 15
(7)
pp. 1208-1219.
10.4103/1673-5374.272571.
|
Kinghorn, KJ;
Groenke, S;
Castillo-Quan, JI;
Woodling, NS;
Li, L;
Sirka, E;
Gegg, M;
... Partridge, L; + view all
(2016)
A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.
JOURNAL OF NEUROSCIENCE
, 36
(46)
pp. 11654-11670.
10.1523/JNEUROSCI.4527-15.2016.
|
Mizielinska, S;
Ridler, CE;
Balendra, R;
Thoeng, A;
Woodling, NS;
Grässer, FA;
Plagnol, V;
... Isaacs, AM; + view all
(2017)
Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration.
Acta Neuropathologica Communications
, 5
, Article 29. 10.1186/s40478-017-0432-x.
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Simone, R;
Balendra, R;
Moens, TG;
Preza, E;
Wilson, KM;
Heslegrave, A;
Woodling, NS;
... Isaacs, AM; + view all
(2018)
G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
EMBO Molecular Medicine
, 10
(1)
pp. 22-31.
10.15252/emmm.201707850.
|
Tesseur, I;
Nguyen, A;
Chang, B;
Li, L;
Woodling, NS;
Wyss-Coray, T;
Luo, J;
(2017)
Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice.
The Journal of Neuroscience
, 37
(17)
pp. 4584-4592.
10.1523/JNEUROSCI.2952-16.2017.
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Woodling, NS;
Colas, D;
Wang, Q;
Minhas, P;
Panchal, M;
Liang, X;
Mhatre, SD;
... Andreasson, KI; + view all
(2016)
Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice.
Brain
, 139
(7)
pp. 2063-2081.
10.1093/brain/aww117.
|
Woodling, NS;
Wang, Q;
Priyam, PG;
Larkin, P;
Shi, J;
Johansson, JU;
Zagol-Ikapitte, I;
... Andreasson, KI; + view all
(2014)
Suppression of Alzheimer-Associated Inflammation by Microglial Prostaglandin-E-2 EP4 Receptor Signaling.
Journal of Neuroscience
, 34
(17)
pp. 5882-5894.
10.1523/JNEUROSCI.0410-14.2014.
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Woodling, NS;
Aleyakpo, B;
Dyson, MC;
Minkley, LJ;
Rajasingam, A;
Dobson, AJ;
Leung, KHC;
... Partridge, L; + view all
(2020)
The neuronal receptor tyrosine kinase Alk is a target for longevity.
Aging Cell
, Article e13137. 10.1111/acel.13137.
(In press).
|
Woodling, NS;
Partridge, L;
(2018)
Parkinson's Disease: Mitochondria Parked at the ER Hit the Snooze Button.
Neuron
, 98
(6)
pp. 1059-1061.
10.1016/j.neuron.2018.06.025.
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Woodling, NS;
Rajasingam, A;
Minkley, LJ;
Rizzo, A;
Partridge, L;
(2020)
Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling.
BMC Biology
, 18
, Article 124. 10.1186/s12915-020-00854-9.
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Yu, Y;
Niccoli, T;
Ren, Z;
Woodling, NS;
Aleyakpo, B;
Szabadkai, G;
Partridge, L;
(2020)
PICALM rescues glutamatergic neurotransmission, behavioural function, and survival in a Drosophila model of Aβ42 toxicity.
Human Molecular Genetics
10.1093/hmg/ddaa125.
(In press).
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