Browse by UCL people
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Number of items: 10.
Article
Angelova, PR;
Choil, ML;
Berezhnov, A;
Horrocks, MH;
Hughes, CD;
De, S;
Rodrigues, M;
... Gandhi, S; + view all
(2020)
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
Cell Death & Differentiation
, 27
pp. 2781-2796.
10.1038/s41418-020-0542-z.
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Choi, Minee L;
Chappard, Alexandre;
Singh, Bhanu P;
Maclachlan, Catherine;
Rodrigues, Margarida;
Fedotova, Evgeniya I;
Berezhnov, Alexey V;
... Gandhi, Sonia; + view all
(2022)
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity.
Nature Neuroscience
10.1038/s41593-022-01140-3.
(In press).
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Choi, ML;
Gandhi, S;
(2018)
Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases.
The FEBS Journal
, 285
(19)
pp. 3631-3644.
10.1111/febs.14587.
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Hall, CE;
Yao, Z;
Choi, M;
Tyzack, GE;
Serio, A;
Luisier, R;
Harley, J;
... Patani, R; + view all
(2017)
Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Cell Reports
, 19
(9)
pp. 1739-1749.
10.1016/j.celrep.2017.05.024.
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Hughes, C;
Choi, ML;
Yi, J-H;
Kim, S-C;
Drews, A;
George-Hyslop, PS;
Bryant, C;
... Klenerman, D; + view all
(2020)
Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death.
Communications Biology
, 3
, Article 79. 10.1038/s42003-020-0792-9.
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Hughes, CD;
Choi, ML;
Ryten, M;
Hopkins, L;
Drews, A;
Botía, JA;
Iljina, M;
... Klenerman, D; + view all
(2019)
Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis.
Acta Neuropathologica
, 137
(1)
pp. 103-120.
10.1007/s00401-018-1907-y.
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Iljina, M;
Hong, L;
Horrocks, MH;
Ludtmann, MH;
Choi, ML;
Hughes, CD;
Ruggeri, FS;
... Klenerman, D; + view all
(2017)
Nanobodies raised against monomeric alpha-synuclein inhibit fibril formation and destabilize toxic oligomeric species.
BMC Biology
, 15
, Article 57. 10.1186/s12915-017-0390-6.
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Iljina, M;
Tosatto, L;
Choi, ML;
Sang, JC;
Ye, Y;
Hughes, CD;
Bryant, CE;
... Klenerman, D; + view all
(2016)
Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein.
Scientific Reports
, 6
, Article 33928. 10.1038/srep33928.
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Ludtmann, MHR;
Angelova, PR;
Horrocks, MH;
Choi, ML;
Rodrigues, M;
Baev, AY;
Berezhnov, AV;
... Gandhi, S; + view all
(2018)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
Nature Communications
, 9
, Article 2293. 10.1038/s41467-018-04422-2.
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Whiten, DR;
Zuo, Y;
Calo, L;
Choi, M-L;
De, S;
Flagmeier, P;
Wirthensohn, DC;
... Horrocks, MH; + view all
(2018)
Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells.
ChemBioChem
, 19
(19)
pp. 2033-2038.
10.1002/cbic.201800209.
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