UCL Discovery
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Number of items: 6.

Article

Atkinson, BN; Steadman, D; Mahy, W; Zhao, Y; Sipthorp, J; Bayle, ED; Svensson, F; ... Fish, PV; + view all (2019) Scaffold-hopping identifies furano[2,3-d]pyrimidine amides as potent Notum inhibitors. Bioorganic & Medicinal Chemistry Letters , Article 126751. 10.1016/j.bmcl.2019.126751. (In press). Green open access
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Atkinson, BN; Steadman, D; Zhao, Y; Sipthorp, J; Vecchia, L; Ruza, RR; Jeganathan, F; ... Fish, PV; + view all (2019) Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen. MedChemComm 10.1039/c9md00096h. (In press). Green open access
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Choudhary, P; Gutteridge, A; Impey, E; Storer, RI; Owen, RM; Whiting, PJ; Bictash, M; (2016) Targeting the cAMP and Transforming Growth Factor-β Pathway Increases Proliferation to Promote Re-Epithelialization of Human Stem Cell-Derived Retinal Pigment Epithelium. Stem Cells Translational Medicine , 5 (7) pp. 925-937. 10.5966/sctm.2015-0247. Green open access
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da Cruz, L; Fynes, K; Georgiadis, O; Kerby, J; Luo, YH; Ahmado, A; Vernon, A; ... Coffey, PJ; + view all (2018) Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration. Nature Biotechnology , 36 (4) pp. 328-337. 10.1038/nbt.4114. Green open access
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Schwartzentruber, J; Foskolou, S; Kilpinen, H; Rodrigues, J; Alasoo, K; Knights, AJ; Patel, M; ... HIPSCI Consortium; + view all (2018) Molecular and functional variation in iPSC-derived sensory neurons. Nature Genetics , 50 pp. 54-61. 10.1038/s41588-017-0005-8. Green open access
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Conference item

Jolly, S; Schuhmacher, L; Lines, G; Mahy, W; Willis, N; Bictash, M; Jones, Y; ... Salinas, P; + view all (2018) Characterisation of the CNS expression and function of Notum, a negative regulator of Wnt signalling pathway. Presented at: Alzheimer’s Research UK Conference, London, UK. Green open access
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