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Number of items: 16.
Article
Bahous, RH;
Jadavji, NM;
Deng, L;
Cosin-Tomas, M;
Lu, J;
Malysheva, O;
Leung, K-Y;
... Rozen, R; + view all
(2017)
High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.
HUMAN MOLECULAR GENETICS
, 26
(5)
pp. 888-900.
10.1093/hmg/ddx004.
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De Castro, SC;
Malhas, A;
Leung, KY;
Gustavsson, P;
Vaux, DJ;
Copp, AJ;
Greene, ND;
(2012)
Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice.
PLoS Genet
, 8
(11)
, Article e1003059. 10.1371/journal.pgen.1003059.
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Essmann, CL;
Martinez-Martinez, D;
Pryor, R;
Leung, K-Y;
Krishnan, KB;
Lui, PP;
Greene, NDE;
... Cabreiro, F; + view all
(2020)
Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans.
Nature Communications
, 11
(1)
, Article 1043. 10.1038/s41467-020-14785-0.
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Greene, ND;
Leung, KY;
Copp, AJ;
(2017)
Inositol, neural tube closure and the prevention of neural tube defects.
Birth Defects Research
, 109
(2)
pp. 68-80.
10.1002/bdra.23533.
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Greene, ND;
Leung, KY;
Gay, V;
Burren, K;
Mills, K;
Chitty, LS;
Copp, AJ;
(2016)
Inositol for the prevention of neural tube defects: a pilot randomised controlled trial.
British Journal of Nutrition
, 115
(6)
pp. 974-983.
10.1017/S0007114515005322.
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Harlan De Crescenzo, A;
Panoutsopoulos, AA;
Tat, L;
Schaaf, Z;
Racherla, S;
Henderson, L;
Leung, K-Y;
... Zarbalis, KS; + view all
(2020)
Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring.
Cerebral Cortex
, Article bhaa248. 10.1093/cercor/bhaa248.
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Leung, Kit-Yi;
Weston, Eleanor;
De Castro, Sandra CP;
Nikolopoulou, Evanthia;
Sudiwala, Sonia;
Savery, Dawn;
Eaton, Simon;
... Greene, Nicholas DE; + view all
(2024)
Association of embryonic inositol status with susceptibility to neural tube defects, metabolite profile, and maternal inositol intake.
FASEB Journal
, 38
(11)
, Article e23738. 10.1096/fj.202400206R.
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Leung, K-Y;
De Castro, SCP;
Santos, C;
Savery, D;
Prunty, H;
Gold-Diaz, D;
Bennett, S;
... Greene, NDE; + view all
(2020)
Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of Non-Ketotic Hyperglycinemia.
Journal of Inherited Metabolic Disease
, 43
(6)
pp. 1186-1198.
10.1002/jimd.12295.
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Leung, K-Y;
Pai, YJ;
Chen, Q;
Santos, C;
Calvani, E;
Sudiwala, S;
Savery, D;
... Greene, NDE; + view all
(2017)
Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure.
Cell Rep
, 21
(7)
pp. 1795-1808.
10.1016/j.celrep.2017.10.072.
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Leung, KY;
De Castro, SC;
Savery, D;
Copp, AJ;
Greene, ND;
(2013)
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse.
Brain: A Journal of Neurology
, 136
(9)
pp. 2836-2841.
10.1093/brain/awt209.
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Medeiros, Tânia Catarina;
Ovciarikova, Jana;
Li, Xianhe;
Krueger, Patrick;
Bartsch, Tim;
Reato, Silvia;
Crow, John C;
... Pernas, Lena; + view all
(2025)
Mitochondria protect against an intracellular pathogen by restricting access to folate.
Science
, 389
(6761)
, Article eadr6326. 10.1126/science.adr6326.
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Mohan, H;
Lenis, MG;
Laurette, EY;
Tejada, O;
Sanghvi, T;
Leung, K-Y;
Cahill, LS;
... Serghides, L; + view all
(2021)
Dolutegravir in pregnant mice is associated with increased rates of fetal defects at therapeutic but not at supratherapeutic levels.
EBioMedicine
, 63
, Article 103167. 10.1016/j.ebiom.2020.103167.
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Pai, YJ;
Leung, KY;
Savery, D;
Hutchin, T;
Prunty, H;
Heales, S;
Brosnan, ME;
... Greene, ND; + view all
(2015)
Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice.
Nat Commun
, 6
, Article 6388. 10.1038/ncomms7388.
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Santos, C;
Pai, YJ;
Mahmood, MR;
Leung, K-Y;
Savery, D;
Waddington, SN;
Copp, AJ;
(2020)
Impaired folate one-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.
Journal of Clinical Investigation
, 130
(3)
pp. 1446-1452.
10.1172/jci132360.
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Scott, TA;
Quintaneiro, LM;
Norvaisas, P;
Lui, PP;
Wilson, MP;
Leung, K-Y;
Herrera-Dominguez, L;
... Cabreiro, F; + view all
(2017)
Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans.
Cell
, 169
(3)
442-456.e18.
10.1016/j.cell.2017.03.040.
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Sudiwala, S;
De Castro, SC;
Leung, KY;
Brosnan, JT;
Brosnan, ME;
Mills, K;
Copp, AJ;
(2016)
Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects.
Biochimie
, 126
pp. 63-70.
10.1016/j.biochi.2016.02.010.
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