Browse by UCL people
Group by: Type | Date
Number of items: 37.
Article
Alsaieedi, A;
Holler, A;
Velica, P;
Bendle, G;
Stauss, HJ;
(2019)
Safety and efficacy of Tet-regulated IL-12 expression in cancer-specific T cells.
Oncoimmunology
, 8
(3)
, Article 1542917. 10.1080/2162402X.2018.1542917.
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Bendle, GM;
Xue, SA;
Holler, A;
Stauss, HJ;
(2007)
A Study of T Cell Tolerance to the Tumor-Associated Antigen MDM2: Cytokines Can Restore Antigen Responsiveness, but Not High Avidity T Cell Function.
PLOS ONE
, 2
(4)
, Article e353. 10.1371/journal.pone.0000353.
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Bray, C;
Wright, D;
Haupt, S;
Thomas, S;
Stauss, H;
Zamoyska, R;
(2018)
Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2.
Frontiers in Immunology
, 9
, Article 2595. 10.3389/fimmu.2018.02595.
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Campbell, M;
Clarke, A;
Symes, A;
Workman, S;
Stauss, H;
Webster, AD;
(2018)
Investigating the Effectiveness, Acceptability and Impact on Healthcare Usage of Providing a Cognitive-Behavioural Based Psychological Therapy Service for Patients with Primary Antibody Deficiency.
Journal of Clinical Immunology
, 38
pp. 214-220.
10.1007/s10875-018-0481-3.
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Campinoti, S;
Gjinovci, A;
Ragazzini, R;
Zanieri, L;
Ariza-McNaughton, L;
Catucci, M;
Boeing, S;
... Bonfanti, P; + view all
(2020)
Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds.
Nature Communications
, 11
, Article 6372. 10.1038/s41467-020-20082-7.
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Cellerai, C;
Harari, A;
Stauss, H;
Yerly, S;
Geretti, AM;
Carroll, A;
Yee, T;
... Kinloch-de Loes, S; + view all
(2011)
Early and Prolonged Antiretroviral Therapy Is Associated with an HIV-1-Specific T-Cell Profile Comparable to That of Long-Term Non-Progressors.
PLOS ONE
, 6
(4)
, Article e18164. 10.1371/journal.pone.0018164.
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Chatterjee, B;
Deng, Y;
Holler, A;
Nunez, N;
Azzi, T;
Vanoaica, LD;
Mueller, A;
... Munz, C; + view all
(2019)
CD8(+) T cells retain protective functions despite sustained inhibitory receptor expression during Epstein-Barr virus infection in vivo.
PLOS Pathogens
, 15
(5)
, Article e1007748. 10.1371/journal.ppat.1007748.
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Cherukuri, A;
Salama, AD;
Mehta, R;
Mohib, K;
Zheng, L;
Magee, C;
Harber, M;
... Rothstein, DM; + view all
(2021)
Transitional B cell cytokines predict renal allograft outcomes.
Science Translational Medicine
, 13
(582)
10.1126/scitranslmed.abe4929.
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Deng, Y;
Chatterjee, B;
Zens, K;
Zdimerova, H;
Müller, A;
Schuhmachers, P;
Ligeon, L-A;
... Münz, C; + view all
(2021)
CD27 is required for protective lytic EBV antigen-specific CD8+ T-cell expansion.
Blood
, 137
(23)
pp. 3225-3236.
10.1182/blood.2020009482.
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Depner, M;
Fuchs, S;
Raabe, J;
Frede, N;
Glocker, C;
Doffinger, R;
Gkrania-Klotsas, E;
... Grimbacher, B; + view all
(2016)
The Extended Clinical Phenotype of 26 Patients with Chronic Mucocutaneous Candidiasis due to Gain-of-Function Mutations in STAT1.
Journal of Clinical Immunology
, 36
(1)
pp. 73-84.
10.1007/s10875-015-0214-9.
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Dertschnig, S;
Evans, P;
Santos e Sousa, P;
Manzo, T;
Ferrer, IR;
Stauss, HJ;
Bennett, CL;
(2020)
Graft-versus-host disease reduces lymph node display of tissue-restricted self-antigens and promotes autoimmunity.
The Journal of Clinical Investigation
10.1172/JCI133102.
(In press).
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Field, AC;
Vink, C;
Gabriel, R;
Al-Subki, R;
Schmidt, M;
Goulden, N;
Stauss, H;
... Qasim, W; + view all
(2013)
Comparison of Lentiviral and Sleeping Beauty Mediated αβ T Cell Receptor Gene Transfer.
PLoS One
, 8
(6)
, Article e68201. 10.1371/journal.pone.0068201.
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Geerdink, JX;
Simons, SO;
Pike, R;
Stauss, HJ;
Heijdra, YF;
Hurst, JR;
(2016)
Differences in systemic adaptive immunity contribute to the `frequent exacerbator' COPD phenotype.
Respiratory Research
, 17
, Article 140. 10.1186/s12931-016-0456-y.
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Ghorashian, S;
Veliça, P;
Chua, I;
McNicol, AM;
Carpenter, B;
Holler, A;
Nicholson, E;
... Stauss, HJ; + view all
(2015)
CD8 T cell tolerance to a tumor-associated self-antigen is reversed by CD4 T cells engineered to express the same T cell receptor.
Journal of Immunology
, 194
(3)
1080 - 1089.
10.4049/jimmunol.1401703.
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Holler, A;
Zech, M;
Ghorashian, S;
Pike, R;
Hotblack, A;
Velica, P;
Xue, S-A;
... Stauss, HJ; + view all
(2016)
Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy.
Haematologica
, 101
(4)
pp. 482-490.
10.3324/haematol.2015.132712.
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Hotblack, A;
Holler, A;
Piapi, A;
Ward, S;
Strauss, HJ;
Bennett, CL;
(2018)
Tumor-resident dendritic cells and macrophages modulate the accumulation of TCR-engineered T cells in melanoma.
Molecular Therapy
, 26
(6)
pp. 1471-1481.
10.1016/j.ymthe.2018.03.011.
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Hou, TZ;
Olbrich, P;
Soto, JML;
Sanchez, B;
Moreno, PS;
Borte, S;
Stauss, HJ;
... Neth, O; + view all
(2018)
Study of an extended family with CTLA-4 deficiency suggests a CD28/CTLA-4 independent mechanism responsible for differences in disease manifestations and severity.
Clinical Immunology
, 188
pp. 94-102.
10.1016/j.clim.2018.01.001.
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Hou, TZ;
Verma, N;
Wanders, J;
Kennedy, A;
Soskic, B;
Janman, D;
Halliday, N;
... Sansom, DM; + view all
(2017)
Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.
Blood
, 129
pp. 1458-1468.
10.1182/blood-2016-10-745174.
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Khan, AB;
Carpenter, B;
Sousa, PSE;
Pospori, C;
Khorshed, R;
Griffin, J;
Veliça, P;
... Chakraverty, R; + view all
(2018)
Redirection to the bone marrow improves T cell persistence and antitumor functions.
The Journal of Clinical Investigation
, 128
(5)
pp. 2010-2024.
10.1172/JCI97454.
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Lopez-Herrera, G;
Tampella, G;
Pan-Hammarström, Q;
Herholz, P;
Trujillo-Vargas, CM;
Phadwal, K;
Simon, AK;
... Grimbacher, B; + view all
(2012)
Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity.
The American Journal of Human Genetics
, 90
(6)
986 - 1001.
10.1016/j.ajhg.2012.04.015.
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McGovern, J;
Holler, A;
Thomas, S;
Stauss, HJ;
(2022)
Forced Fox-P3 expression can improve the safety and antigen-specific function of engineered regulatory T cells.
Journal of Autoimmunity
, 132
, Article 102888. 10.1016/j.jaut.2022.102888.
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McGovern, JL;
Wright, GP;
Stauss, HJ;
(2017)
Engineering Specificity and Function of Therapeutic Regulatory T Cells.
Front. Immunol.
, 8
, Article 1517. 10.3389/fimmu.2017.01517.
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Mehler, VJ;
Burns, CJ;
Stauss, H;
Francis, RJ;
Moore, ML;
(2020)
Human iPSC-Derived Neural Crest Stem Cells Exhibit Low Immunogenicity.
Molecular Therapy: Methods & Clinical Development
, 16
pp. 161-171.
10.1016/j.omtm.2019.12.015.
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Otano, I;
Escors, D;
Schurich, A;
Singh, H;
Robertson, F;
Davidson, BR;
Fusai, G;
... Maini, MK; + view all
(2018)
Molecular Recalibration of PD-1+ Antigen-Specific T Cells from Blood and Liver.
Molecular Therapy
10.1016/j.ymthe.2018.08.013.
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Peng, Y;
Felce, SL;
Dong, D;
Penkava, F;
Mentzer, AJ;
Yao, X;
Liu, G;
... Dong, T; + view all
(2021)
An immunodominant NP105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.
Nature Immunology
10.1038/s41590-021-01084-z.
(In press).
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Pike, R;
Thomas, N;
Workman, S;
Ambrose, L;
Guzman, D;
Sivakumaran, S;
Johnson, M;
... Stauss, HJ; + view all
(2016)
PD1-Expressing T Cell Subsets Modify the Rejection Risk in Renal Transplant Patients.
Frontiers in Immunology
, 7
, Article 126. 10.3389/fimmu.2016.00126.
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Rees-Spear, C;
Muir, L;
Griffith, SA;
Heaney, J;
Aldon, Y;
Snitselaar, JL;
Thomas, P;
... McCoy, LE; + view all
(2021)
The effect of spike mutations on SARS-CoV-2 neutralization.
Cell Reports
, Article 108890. 10.1016/j.celrep.2021.108890.
(In press).
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Schmidt, NM;
Wing, PAC;
Diniz, MO;
Pallett, LJ;
Swadling, L;
Harris, JM;
Burton, AR;
... Maini, MK; + view all
(2021)
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.
Nature Communications
, 12
, Article 2814. 10.1038/s41467-021-22967-7.
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Sillito, F;
Holler, A;
Stauss, HJ;
(2020)
Engineering CD4+ T Cells to Enhance Cancer Immunity.
Cells
, 9
(7)
, Article 1721. 10.3390/cells9071721.
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Śledzińska, A;
Vila de Mucha, M;
Bergerhoff, K;
Hotblack, A;
Demane, DF;
Ghorani, E;
Akarca, AU;
... Quezada, SA; + view all
(2020)
Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4⁺ T Cells.
Immunity
, 52
(1)
151-166.e6.
10.1016/j.immuni.2019.12.007.
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Stauss, HJ;
(2017)
Turn to TCRs when CARs fail.
Oncotarget
, 8
(8)
pp. 12538-12539.
10.18632/oncotarget.15088.
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Stauss, HJ;
Tran, MGB;
(2020)
TCR Gene Therapy: Challenges, Opportunities, and Future Directions.
Cells
, 9
(12)
, Article 2567. 10.3390/cells9122567.
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Thomas, S;
Mohammed, F;
Reijmers, RM;
Woolston, A;
Stauss, T;
Kennedy, A;
Stirling, D;
... Stauss, HJ; + view all
(2019)
Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function.
Nature Communications
, 10
(1)
, Article 4451. 10.1038/s41467-019-12441-w.
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Uttenthal, B;
Martinez-Davila, I;
Ivey, A;
Craddock, C;
Chen, F;
Virchis, A;
Kottaridis, P;
... Morris, EC; + view all
(2014)
Wilms' Tumour 1 (WT1) peptide vaccination in patients with acute myeloid leukaemia induces short-lived WT1-specific immune responses.
Br J Haematol
, 164
(3)
366 - 375.
10.1111/bjh.12637.
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von Baumgarten, Louisa;
Stauss, Hans J;
Lünemann, Jan D;
(2023)
Synthetic Cell-Based Immunotherapies for Neurologic Diseases.
Neurol Neuroimmunol Neuroinflamm
, 10
(5)
, Article e200139. 10.1212/NXI.0000000000200139.
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Conference item
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Morris, EC;
Tendeiro-Rego, R;
Richardson, R;
Fox, TA;
Sillito, F;
Holler, A;
Thomas, S;
... Stauss, H; + view all
(2019)
A Phase I Study Evaluating the Safety and Persistence of Allorestricted WT1-TCR Gene Modified Autologous T Cells in Patients with High-Risk Myeloid Malignancies Unsuitable for Allogeneic Stem Cell Transplantation.
Presented at: 61st ASH Annual Meeting, Orlando, FL, USA.
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Thesis
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Stavrou, M;
(2016)
CAR Gene Transfer to Generate Antigen Specific Regulators.
Doctoral thesis , UCL (University College London).
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