Browse by UCL people
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Number of items: 9.
Article
Aldous, Sarah G;
Smith, Edward J;
Landles, Christian;
Osborne, Georgina F;
Cañibano-Pico, Maria;
Nita, Iulia M;
Phillips, Jemima;
... Bates, Gillian P; + view all
(2024)
A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
Brain
, 147
(5)
pp. 1784-1798.
10.1093/brain/awae063.
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Bondulich, MK;
Jolinon, N;
Osborne, GF;
Smith, EJ;
Rattray, I;
Neueder, A;
Sathasivam, K;
... Bates, GP; + view all
(2017)
Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington's disease mice.
Scientific Reports
, 7
, Article 14275. 10.1038/s41598-017-14290-3.
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Fienko, Sandra;
Landles, Christian;
Sathasivam, Kirupa;
McAteer, Sean J;
Milton, Rebecca E;
Osborne, Georgina F;
Smith, Edward J;
... Bates, Gillian P; + view all
(2022)
Alternative processing of human HTT mRNA with implications for Huntington's disease therapeutics.
Brain
10.1093/brain/awac241.
(In press).
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Ghosh, R;
Wood-Kaczmar, A;
Dobson, L;
Smith, EJ;
Sirinathsinghji, EC;
Kriston-Vizi, J;
Hargreaves, IP;
... Tabrizi, SJ; + view all
(2020)
Expression of mutant exon 1 huntingtin fragments in human neural stem cells and neurons causes inclusion formation and mitochondrial dysfunction.
FASEB Journal
10.1096/fj.201902277RR.
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Landles, C;
Milton, RE;
Ali, N;
Flomen, R;
Flower, M;
Schindler, F;
Gomez-Paredes, C;
... Bates, GP; + view all
(2020)
Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington’S Disease Model.
Brain Communications
, 2
(2)
, Article fcaa066. 10.1093/braincomms/fcaa066.
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Lu, M;
Banetta, L;
Young, LJ;
Smith, EJ;
Bates, GP;
Zaccone, A;
Schierle, GSK;
... Kaminski, CF; + view all
(2019)
Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly.
Journal of Biological Chemistry
, 294
(1)
pp. 257-268.
10.1074/jbc.RA118.003500.
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Rattray, I;
Smith, EJ;
Crum, WR;
Walker, TA;
Gale, R;
Bates, GP;
Modo, M;
(2017)
Correlations of Behavioral Deficits with Brain Pathology Assessed through Longitudinal MRI and Histopathology in the HdhQ150/Q150 Mouse Model of Huntington’s Disease.
PLOS ONE
, 12
(1)
, Article e0168556. 10.1371/journal.pone.0168556.
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Smith, EJ;
Farshim, PP;
Flomen, R;
Jones, ST;
McAteer, SJ;
Deverman, BE;
Gradinaru, V;
(2021)
Use of high-content imaging to quantify transduction of AAV-PHP viruses in the brain following systemic delivery.
Brain Communications
, 3
(2)
10.1093/braincomms/fcab105.
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Zhou, Y;
Peskett, TR;
Landles, C;
Warner, JB;
Sathasivam, K;
Smith, EJ;
Chen, S;
... Saibil, HR; + view all
(2021)
Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington’s disease.
Acta Neuropathologica Communications
, 9
, Article 70. 10.1186/s40478-021-01172-z.
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