Browse by UCL people
Group by: Type | Date
Number of items: 16.
2024
Flaherty, Cole C;
Phillips, Ian R;
Janmohamed, Azara;
Shephard, Elizabeth A;
(2024)
Living with trimethylaminuria and body and breath malodour: personal perspectives.
BMC Public Health
, 24
, Article 222. 10.1186/s12889-024-17685-w.
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2023
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Phillips, Ian R;
Veeravalli, Sunil;
Khadayate, Sanjay;
Shephard, Elizabeth A;
(2023)
Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress response, unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism.
PLOS ONE
, 18
(6)
, Article e0286692. 10.1371/journal.pone.0286692.
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2022
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Veeravalli, Sunil;
Dorsa, Varshavi;
Scott, Flora;
Dorna, Varshavi;
Pullen, Frank;
Kirill, Veselkov;
Phillips, Ian;
... Shephard, Elizabeth; + view all
(2022)
Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition.
Frontiers in Physiology
, 13
, Article 859681. 10.3389/fphys.2022.859681.
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2020
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Phillips, I;
Shephard, EA;
(2020)
Flavin-containing monooxygenase 3 (FMO3): genetic variants and their consequences for drug metabolism and disease.
Xenobiotica
, 50
(1)
pp. 19-33.
10.1080/00498254.2019.1643515.
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Phillips, IR;
Shephard, EA;
(2020)
Flavin-containing monooxygenases: new structures from old proteins.
Nature Structural & Molecular Biology
, 27
pp. 3-4.
10.1038/s41594-019-0356-1.
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Veeravalli, S;
Phillips, IR;
Freire, RT;
Varshavi, D;
Everett, JR;
Shephard, EA;
(2020)
Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.
Drug Metabolism and Disposition
, 48
(5)
pp. 378-385.
10.1124/dmd.119.089995.
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2019
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Phillips, IR;
Shephard, EA;
(2019)
Endogenous Roles of Mammalian Flavin-Containing Monooxygenases.
Catalysts
, 9
(12)
, Article 1001. 10.3390/catal9121001.
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2018
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Varshavi, D;
Scott, F;
Varshavi, D;
Veeravalli, SK;
Phillips, I;
Veselkov, K;
Strittmatter, N;
... Everett, JR; + view all
(2018)
Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice.
Frontiers in Molecular Biosciences
, 5
, Article 28. 10.3389/fmolb.2018.00028.
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Veeravalli, S;
Karu, K;
Scott, F;
Fennema, D;
Phillips, IR;
Shephard, EA;
(2018)
Effect of Flavin-Containing Monooxygenase Genotype, Mouse Strain, and Gender on Trimethylamine N-oxide Production, Plasma Cholesterol Concentration, and an Index of Atherosclerosis.
Drug Metabolism and Disposition
, 46
(1)
pp. 20-25.
10.1124/dmd.117.077636.
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2017
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Scott, F;
Gonzalez Malagon, SG;
O'Brien, BA;
Fennema, D;
Veeravalli, S;
Phillips, IR;
Coveney, CR;
(2017)
Identification of flavin-containing monooxygenase 5 (FMO5) as a regulator of glucose homeostasis and a potential sensor of gut bacteria.
Drug Metabolism and Disposition
, 45
(9)
pp. 982-989.
10.1124/dmd.117.076612.
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Veeravalli, S;
Karu, K;
Phillips, IR;
Shephard, EA;
(2017)
A highly sensitive liquid chromatography electrospray ionization mass spectrometry method for quantification of TMA, TMAO and creatinine in mouse urine.
MethodsX
, 4
pp. 310-319.
10.1016/j.mex.2017.09.004.
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2016
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Bartlett, MJ;
Shephard, EA;
(2016)
The integration and interpretation of pharmacogenomics. A comparative study between the United States of America and Europe: towards better health care.
Drug Metabolism and Personalized Therapy
, 31
(2)
pp. 91-96.
10.1515/dmpt-2015-0044.
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Dona, AC;
Kyriakides, M;
Scott, F;
Shephard, EA;
Varshavi, D;
Veselkov, K;
Everett, JR;
(2016)
A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments.
Computational and Structural Biotechnology Journal
10.1016/j.csbj.2016.02.005.
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Fennema, D;
Phillips, IR;
Shephard, EA;
(2016)
Trimethylamine and trimethylamine N-oxide, a flavin-containing monooxygenase 3 (FMO3)-mediated host-microbiome metabolic axis implicated in health and disease.
Drug Metabolism and Disposition
, 44
pp. 1839-1850.
10.1124/dmd.116.070615.
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Phillips, IR;
Shephard, EA;
(2016)
Drug metabolism by flavin-containing monooxygenases of human and mouse.
Expert Opinion in Drug Metabolism and Toxicology
, 13
(2)
pp. 167-181.
10.1080/17425255.2017.1239718.
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2015
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Gonzalez Malagon, SG;
Melidoni, AN;
Hernandez, D;
Omar, BA;
Houseman, L;
Veeravalli, S;
Scott, F;
... Shephard, EA; + view all
(2015)
The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing.
Biochemical Pharmacology
, 96
(3)
pp. 267-277.
10.1016/j.bcp.2015.05.013.
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