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Number of items: 20.
Article
Abedini, A;
Cao, P;
Plesner, A;
Zhang, J;
He, M;
Derk, J;
Patil, SA;
... Schmidt, AM; + view all
(2018)
RAGE binds preamyloid IAPP intermediates and mediates pancreatic beta cell proteotoxicity.
Journal of Clinical Investigation
, 128
(2)
pp. 682-698.
10.1172/JCI85210.
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Abedini, A;
Plesner, A;
Cao, P;
Ridgway, Z;
Zhang, J;
Tu, L-H;
Middleton, CT;
... Schmidt, AM; + view all
(2016)
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics.
eLife
, 5
, Article e12977. 10.7554/eLife.12977.
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Akter, R;
Abedini, A;
Ridgway, Z;
Zhang, X;
Kleinberg, J;
Schmidt, AM;
Raleigh, DP;
(2017)
Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?
Israel Journal of Chemistry
, 57
(7-8)
pp. 750-761.
10.1002/ijch.201600081.
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Akter, R;
Zhyvoloup, A;
Zheng, B;
Bhatia, SR;
Raleigh, DP;
(2019)
The triphenylmethane dye brilliant blue G is only moderately effective at inhibiting amyloid formation by human amylin or at disaggregating amylin amyloid fibrils, but interferes with amyloid assays; Implications for inhibitor design.
PLoS One
, 14
(8)
, Article e0219130. 10.1371/journal.pone.0219130.
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Baum, J;
Raleigh, D;
(2018)
Protein Aggregation.
[Editorial comment].
Protein Science
, 27
(7)
pp. 1149-1150.
10.1002/pro.3446.
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Brar, GS;
Barrow, BM;
Watson, M;
Griesbach, R;
Choung, E;
Welch, A;
Ruzsicska, B;
... Zraika, S; + view all
(2017)
Neprilysin Is Required for Angiotensin-(1-7)'s Ability to Enhance Insulin Secretion via Its Proteolytic Activity to Generate Angiotensin-(1-2).
Diabetes
, 66
(8)
pp. 2201-2212.
10.2337/db16-1318.
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Nagarajan, S;
Xiao, S;
Raleigh, DP;
Dyer, RB;
(2018)
Heterogeneity in the Folding of Villin Headpiece Subdomain HP36.
Journal of Physical Chemistry B
, 122
(49)
pp. 11640-11648.
10.1021/acs.jpcb.8b07683.
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Peran, I;
Holehouse, AS;
Carrico, IS;
Pappu, RV;
Bilsel, O;
Raleigh, DP;
(2019)
Unfolded states under folding conditions accommodate sequence-specific conformational preferences with random coil-like dimensions.
Proceedings of the National Academy of Sciences of the United States of America
, 116
(25)
pp. 12301-12310.
10.1073/pnas.1818206116.
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Raj, S;
Nazemidashtarjandi, S;
Kim, J;
Joffe, L;
Zhang, X;
Singh, A;
Mor, V;
... Farnoud, AM; + view all
(2017)
Changes in glucosylceramide structure affect virulence and membrane biophysical properties of Cryptococcus neoformans.
Biochimica et Biophysica Acta (BBA) - Biomembranes
, 1859
(11)
pp. 2224-2233.
10.1016/j.bbamem.2017.08.017.
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Ridgway, Z;
Eldrid, CFS;
Zhyvoloup, A;
Ben-Younis, A;
Noh, D;
Thalassinos, K;
Raleigh, DP;
(2020)
Analysis of Proline Substitutions Reveals the Plasticity and Sequence Sensitivity of Human IAPP Amyloidogenicity and Toxicity.
Biochemistry
, 59
(6)
pp. 742-754.
10.1021/acs.biochem.9b01109.
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Serrano, AL;
Lomont, JP;
Tu, L-H;
Raleigh, DP;
Zanni, MT;
(2017)
A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP.
Journal of the American Chemical Society
, 139
(46)
pp. 16748-16758.
10.1021/jacs.7b08830.
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Stenzoski, NE;
Luang, B;
Holehouse, AS;
Raleigh, DP;
(2018)
The Unfolded State of the C-Terminal Domain of L9 Expands at Low but Not at Elevated Temperatures.
Biophysical Journal
, 115
(4)
pp. 655-663.
10.1016/j.bpj.2018.07.013.
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Watson, MD;
Monroe, J;
Raleigh, DP;
(2018)
Size-Dependent Relationships between Protein Stability and Thermal Unfolding Temperature Have Important Implications for Analysis of Protein Energetics and High-Throughput Assays of Protein-Ligand Interactions.
Journal of Physical Chemistry B
, 122
(21)
pp. 5278-5285.
10.1021/acs.jpcb.7b05684.
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Watson, MD;
Peran, I;
Raleigh, DP;
(2016)
A Non-perturbing Probe of Coiled Coil Formation Based on Electron Transfer Mediated Fluorescence Quenching.
Biochemistry
, 55
(26)
pp. 3685-3691.
10.1021/acs.biochem.6b00270.
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Watson, MD;
Peran, I;
Zou, J;
Bilse, O;
Raleigh, DP;
(2017)
Selenomethionine Quenching of Tryptophan Fluorescence Provides a Simple Probe of Protein Structure.
Biochemistry
, 56
(8)
pp. 1085-1094.
10.1021/acs.biochem.6b01000.
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Young, LM;
Tu, LH;
Raleigh, DP;
Ashcroft, AE;
Radford, SE;
(2017)
Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers.
Chemical Science
, 8
(7)
pp. 5030-5040.
10.1039/c7sc00620a.
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Zhang, X;
London, E;
Raleigh, DP;
(2018)
Sterol Structure Strongly Modulates Membrane-Islet Amyloid Polypeptide Interactions.
Biochemistry
, 57
(12)
pp. 1868-1879.
10.1021/acs.biochem.7b01190.
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Zhang, X;
St Clair, JR;
London, E;
Raleigh, DP;
(2017)
Islet Amyloid Polypeptide Membrane Interactions: Effects of Membrane Composition.
Biochemistry
, 56
(2)
pp. 376-390.
10.1021/acs.biochem.6b01016.
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Zhang, Y;
Kitazawa, S;
Peran, I;
Stenzoski, N;
McCallum, SA;
Raleigh, DP;
Royer, CA;
(2016)
High Pressure ZZ-Exchange NMR Reveals Key Features of Protein Folding Transition States.
Journal of the American Chemical Society
, 138
(46)
pp. 15260-15266.
10.1021/jacs.6b09887.
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Zou, J;
Song, B;
Simmerling, C;
Raleigh, D;
(2016)
Experimental and Computational Analysis of Protein Stabilization by Gly-to-D-Ala Substitution: A Convolution of Native State and Unfolded State Effects.
Journal of the American Chemical Society
, 138
(48)
pp. 15682-15689.
10.1021/jacs.6b09511.
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