Browse by UCL people
Group by: Type | Date
Number of items: 16.
2024
Bonjorno, Andressa Francielli;
Pavan, Aline Renata;
Fernandes, Guilherme FS;
Scarim, Caue Benito;
Castagnolo, Daniele;
Dos Santos, Jean Leandro;
(2024)
BacPROTACs targeting Clp protease: a promising strategy for anti-mycobacterial drug discovery.
Frontiers in Chemistry
, 12
, Article 1358539. 10.3389/fchem.2024.1358539.
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Fernandes, Guilherme FS;
Kim, Seong-Heun;
Castagnolo, Daniele;
(2024)
Harnessing biocatalysis as a green tool in antibiotic synthesis and discovery.
RSC Advances
, 14
(41)
pp. 30396-30410.
10.1039/d4ra04824e.
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Kim, Seong-Heun;
Hind, Charlotte K;
Fernandes, Guilherme FS;
Wu, Jingyue;
Semenya, Dorothy;
Clifford, Melanie;
Marsh, Caleb;
... Castagnolo, Daniele; + view all
(2024)
Development of Novel Membrane Disrupting Lipoguanidine Compounds Sensitizing Gram-Negative Bacteria to Antibiotics.
ACS Medicinal Chemistry Letters
10.1021/acsmedchemlett.3c00460.
(In press).
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Maringolo Ribeiro, Camila;
Augusto Roque-Borda, Cesar;
Carolina Franzini, Maria;
Fernanda Manieri, Karyn;
Manaia Demarqui, Fernanda;
Leite Campos, Débora;
Temperani Amaral Machado, Rachel;
... Rogério Pavan, Fernando; + view all
(2024)
Liposome-siderophore conjugates loaded with moxifloxacin serve as a model for drug delivery against Mycobacterium tuberculosis.
International Journal of Pharmaceutics
, 655
, Article 124050. 10.1016/j.ijpharm.2024.124050.
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2023
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Anselmi, Silvia;
Carvalho, Alexandra TP;
Serrano-Sanchez, Angela;
Ortega-Roldan, Jose L;
Caswell, Jill;
Omar, Iman;
Perez-Ortiz, Gustavo;
... Castagnolo, Daniele; + view all
(2023)
Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides.
ACS Catalysis
, 13
(7)
pp. 4742-4751.
10.1021/acscatal.3c00372.
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Fernandes, Guilherme Felipe Santos;
Scarim, Cauê Benito;
Kim, Seong-Heun;
Wu, Jingyue;
Castagnolo, Daniele;
(2023)
Oxazolidinones as versatile scaffolds in medicinal chemistry.
RSC Medicinal Chemistry
10.1039/d2md00415a.
(In press).
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Finger, Vladimir;
Kufa, Martin;
Soukup, Ondrej;
Castagnolo, Daniele;
Roh, Jaroslav;
Korabecny, Jan;
(2023)
Pyrimidine derivatives with antitubercular activity.
European Journal of Medicinal Chemistry
, 246
, Article 114946. 10.1016/j.ejmech.2022.114946.
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Xiang, Haoyue;
Ferla, Salvatore;
Varricchio, Carmine;
Brancale, Andrea;
Brown, Nicola L;
Black, Gary W;
Turner, Nicholas J;
(2023)
Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts.
ACS Catalysis
, 13
(5)
pp. 3370-3378.
10.1021/acscatal.2c05902.
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Zamberlan, Francesco;
Castagnolo, Daniele;
Sarkar, Paramita;
Schultz, Dani;
(2023)
Looking back and moving forward in medicinal chemistry.
Nature Communications
, 14
, Article 4299. 10.1038/s41467-023-39949-6.
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2022
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Fernandes, Guilherme FS;
Thompson, Andrew M;
Castagnolo, Daniele;
Denny, William A;
Dos Santos, Jean L;
(2022)
Tuberculosis Drug Discovery: Challenges and New Horizons.
Journal of Medicinal Chemistry
, 65
(11)
pp. 7489-7531.
10.1021/acs.jmedchem.2c00227.
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Semenya, D;
Touitou, M;
Ribeiro, CM;
Pavan, FR;
Pisano, L;
Singh, V;
Chibale, K;
... Castagnolo, D; + view all
(2022)
Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria.
ACS Medicinal Chemistry Letters
, 13
(1)
pp. 63-69.
10.1021/acsmedchemlett.1c00431.
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Semenya, Dorothy;
Touitou, Meir;
Masci, Domiziana;
Ribeiro, Camila Maringolo;
Pavan, Fernando Rogerio;
Dos Santos Fernandes, Guilherme Felipe;
Gianibbi, Beatrice;
... Castagnolo, Daniele; + view all
(2022)
Tapping into the antitubercular potential of 2,5-dimethylpyrroles: A structure-activity relationship interrogation.
European Journal of Medicinal Chemistry
, 237
, Article 114404. 10.1016/j.ejmech.2022.114404.
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Zhao, Fei;
Lauder, Kate;
Liu, Siyu;
Finnigan, James D;
Charnock, Simon BR;
Charnock, Simon J;
Castagnolo, Daniele;
(2022)
Chemoenzymatic Cascades for the Enantioselective Synthesis of β-Hydroxysulfides Bearing a Stereocentre at the C−O or C−S Bond by Ketoreductases.
Angewandte Chemie International Edition
, 61
(31)
, Article e202202363. 10.1002/anie.202202363.
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Zhao, Fei;
Lauder, Kate;
Liu, Siyu;
Finnigan, James D;
Charnock, Simon BR;
Charnock, Simon J;
Castagnolo, Daniele;
(2022)
Chemoenzymatic Cascades for the Enantioselective Synthesis of β‐Hydroxysulfides Bearing a Stereocentre at the C−O or C−S Bond by Ketoreductases.
Angewandte Chemie
, 134
(31)
, Article e202202363. 10.1002/ange.202202363.
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2020
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Spizzichino, S;
Mattedi, G;
Lauder, K;
Valle, C;
Aouadi, W;
Canard, B;
Decroly, E;
... Castagnolo, D; + view all
(2020)
Design, Synthesis and Discovery of N,N'-Carbazoyl-aryl-urea Inhibitors of Zika NS5 Methyltransferase and Virus Replication.
ChemMedChem
, 15
(4)
pp. 385-390.
10.1002/cmdc.201900533.
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Touitou, M;
Manetti, F;
Ribeiro, CM;
Pavan, FR;
Scalacci, N;
Zrebna, K;
Begum, N;
... Castagnolo, D; + view all
(2020)
Improving the Potency of N-Aryl-2,5-dimethylpyrroles against Multidrug-Resistant and Intracellular Mycobacteria.
ACS Medicinal Chemistry Letters
, 11
(5)
pp. 638-644.
10.1021/acsmedchemlett.9b00515.
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