Browse by UCL people
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Number of items: 19.
Article
Adib, R;
Montgomery, JM;
Atherton, J;
O'Regan, L;
Richards, MW;
Straatman, KR;
Roth, D;
... Fry, AM; + view all
(2019)
Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression.
Science Signaling
, 12
(594)
, Article eaaw2939. 10.1126/scisignal.aaw2939.
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Atherton, J;
Hummel, JJ;
Olieric, N;
Locke, J;
Peña, A;
Rosenfeld, SS;
Steinmetz, MO;
... Moores, CA; + view all
(2020)
The mechanism of kinesin inhibition by kinesin binding protein.
eLife
, 9
, Article e61481. 10.7554/eLife.61481.
(In press).
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Atherton, J;
Jiang, K;
Stangier, MM;
Luo, Y;
Hua, S;
Houben, K;
van Hooff, JJE;
... Akhmanova, A; + view all
(2017)
A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nature Structural & Molecular Biology
, 24
(11)
pp. 931-943.
10.1038/nsmb.3483.
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Atherton, J;
Stouffer, M;
Francis, F;
Moores, CA;
(2018)
Microtubule architecture in vitro and in cells revealed by cryo-electron tomography.
Acta Crystallographica Section D - Structural Biology
, D74
pp. 572-584.
10.1107/S2059798318001948.
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Atherton, J;
Yu, I-M;
Cook, A;
Muretta, JM;
Joseph, A;
Major, J;
Sourigues, Y;
... Moores, CA; + view all
(2017)
The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.
eLIFE
, 6
, Article e27793. 10.7554/eLife.27793.
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Bullen, A;
Taylor, RR;
Kachar, B;
Moores, C;
Fleck, RA;
Forge, A;
(2014)
Inner ear tissue preservation by rapid freezing: Improving fixation by high-pressure freezing and hybrid methods.
Hearing Research
, 315
pp. 49-60.
10.1016/j.heares.2014.06.006.
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Bullen, A;
West, T;
Moores, C;
Ashmore, J;
Fleck, RA;
MacLellan-Gibson, K;
Forge, A;
(2015)
Association of intracellular and synaptic organization in cochlear inner hair cells revealed by 3D electron microscopy.
Journal of Cell Science
, 128
(14)
pp. 2529-2540.
10.1242/jcs.170761.
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Locke, J;
Joseph, AP;
Peña, A;
Möckel, MM;
Mayer, TU;
Topf, M;
Moores, CA;
(2017)
Structural basis of human kinesin-8 function and inhibition.
Proceedings of the National Academy of Sciences of the United States of America
, 114
(45)
E9539-E9548.
10.1073/pnas.1712169114.
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Manka, SW;
Moores, CA;
(2020)
Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation.
EMBO Reports
, Article e51534. 10.15252/embr.202051534.
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Manka, SW;
Moores, CA;
(2018)
Microtubule structure by cryo-EM: snapshots of dynamic instability.
Essays in Biochemistry
, 62
(6)
pp. 737-751.
10.1042/EBC20180031.
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Manka, SW;
Moores, CA;
(2018)
The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability.
Nature Structural & Molecular Biology
, 25
(7)
pp. 607-615.
10.1038/s41594-018-0087-8.
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Peña, A;
Sweeney, A;
Cook, AD;
Topf, M;
Moores, CA;
(2020)
Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure
10.1016/j.str.2020.01.013.
(In press).
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Vemu, A;
Atherton, J;
Spector, JO;
Moores, CA;
Roll-Mecak, A;
(2017)
Tubulin isoform composition tunes microtubule dynamics.
Molecular Biology of the Cell
, 28
(25)
pp. 3563-3725.
10.1091/mbc.E17-02-0124.
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Vemu, A;
Atherton, J;
Spector, JO;
Szyk, A;
Moores, CA;
Roll-Mecak, A;
(2016)
Structure and Dynamics of Single-isoform Recombinant Neuronal Human Tubulin.
Journal of Biological Chemistry
, 291
(25)
pp. 12907-12915.
10.1074/jbc.C116.731133.
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von Loeffelholz, O;
Pena, A;
Drummond, DR;
Cross, R;
Moores, CA;
(2019)
Cryo-EM Structure (4.5-angstrom) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance.
Journal of Molecular Biology
, 431
(4)
pp. 864-872.
10.1016/j.jmb.2019.01.011.
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Von Loeffelholz, O;
Purkiss, A;
Cao, L;
Kjaer, S;
Kogata, N;
Romet-Lemonne, G;
Way, M;
(2020)
Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biology Open
10.1242/bio.054304.
(In press).
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von Loeffelholz, O;
Venables, NA;
Drummond, DR;
Katsuki, M;
Cross, R;
Moores, CA;
(2017)
Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics.
Nature Communications
, 8
, Article 2110. 10.1038/s41467-017-02241-5.
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Zeeshan, M;
Brady, D;
Stanway, RR;
Moores, CA;
Holder, AA;
Tewari, R;
(2020)
Plasmodium berghei Kinesin-5 Associates With the Spindle Apparatus During Cell Division and Is Important for Efficient Production of Infectious Sporozoites.
Frontiers in Cellular and Infection Microbiology
, 10
, Article 583812. 10.3389/fcimb.2020.583812.
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Zeeshan, M;
Ferguson, DJP;
Abel, S;
Burrrell, A;
Rea, E;
Brady, D;
Daniel, E;
... Tewari, R; + view all
(2019)
Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.
Life Science Alliance
, 2
(4)
, Article e201900488. 10.26508/lsa.201900488.
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