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Number of items at this level: 31.

Article

Asante, EA; Grimshaw, A; Smidak, M; Jakubcova, T; Tomlinson, A; Jeelani, A; Hamdan, S; ... Collinge, J; + view all (2015) Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS. PLOS Pathogens , 11 (7) , Article e1004953. 10.1371/journal.ppat.1004953. Green open access
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Asante, EA; Linehan, JM; Smidak, M; Tomlinson, A; Grimshaw, A; Jeelani, A; Jakubcova, T; ... Collinge, J; + view all (2013) Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein. PLoS Pathog , 9 (9) , Article e1003643. 10.1371/journal.ppat.1003643. Green open access
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Asante, EA; Linehan, JM; Tomlinson, AD; Jakubcova, T; Hamdan, S; Grimshaw, A; Smidak, M; ... Collinge, J; + view all (2020) Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. PLOS Biology , 18 (6) , Article e3000725. 10.1371/journal.pbio.3000725. Green open access
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Asante, EA; Smidak, M; Grimshaw, A; Houghton, R; Tomlinson, A; Jeelani, A; Jakubcova, T; ... Collinge, J; + view all (2015) A naturally occurring variant of the human prion protein completely prevents prion disease. Nature , 522 pp. 478-481. 10.1038/nature14510. Green open access
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Bjorkqvist, M; Wild, EJ; Thiele, J; Silvestroni, A; Andre, R; Lahiri, N; Raibon, E; ... Tabrizi, SJ; + view all (2008) A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease. Journal of Experimental Medicine , 205 (8) 1869 - 1877. 10.1084/jem.20080178. Green open access
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Castro-Seoane, R; Hummerich, H; Sweeting, T; Tattum, MH; Linehan, JM; Fernandez de Marco, M; Brandner, S; ... Klöhn, PC; + view all (2012) Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. PLoS Pathogens , 8 (2) , Article e1002538. 10.1371/journal.ppat.1002538. Green open access
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DeCordova, S; Abdelgany, A; Murugaiah, V; Pathan, AA; Nayak, A; Walker, T; Shastri, A; ... Kishore, U; + view all (2019) Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients. Immunobiology , 224 (5) pp. 625-631. 10.1016/j.imbio.2019.07.006. Green open access
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Gill, ON; Spencer, Y; Richard-Loendt, A; Kelly, C; Brown, D; Sinka, K; Andrews, N; ... Brandner, S; + view all (2020) Prevalence in Britain of abnormal prion protein in human appendices before and after exposure to the cattle BSE epizootic. Acta Neuropathologica 10.1007/s00401-020-02153-7. (In press). Green open access
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Gill, ON; Spencer, Y; Richard-Loendt, A; Kelly, C; Dabaghian, R; Boyes, L; Linehan, J; ... Brandner, S; + view all (2013) Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey. BMJ , 347 , Article f5675. 10.1136/bmj.f5675. Green open access
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Joiner, S; Asante, EA; Linehan, JM; Brock, L; Brandner, S; Bellworthy, SJ; Simmons, MM; ... Wadsworth, JDF; + view all (2018) Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein. Journal of the Neurological Sciences , 386 pp. 4-11. 10.1016/j.jns.2017.12.038. Green open access
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Jones, E; Hummerich, H; Viré, E; Uphill, J; Dimitriadis, A; Speedy, H; Campbell, T; ... Mead, S; + view all (2020) Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study. The Lancet Neurology , 19 (10) pp. 840-848. 10.1016/S1474-4422(20)30273-8. Green open access
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Klyubin, I; Nicoll, AJ; Khalili-Shirazi, A; Farmer, M; Canning, S; Mably, A; Linehan, J; ... Collinge, J; + view all (2014) Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease Aβ Synaptotoxicity. J Neurosci , 34 (18) 6140 - 6145. 10.1523/JNEUROSCI.3526-13.2014. Green open access
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McKinnon, C; Goold, R; Andre, R; Devoy, A; Ortega, Z; Moonga, J; Linehan, JM; ... Tabrizi, SJ; + view all (2016) Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system. Acta Neuropathologica , 131 (3) pp. 411-425. 10.1007/s00401-015-1508-y. Green open access
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Mead, S; Gandhi, S; Beck, J; Caine, D; Gallujipali, D; Carswell, C; Hyare, H; ... Collinge, J; + view all (2013) A Novel Prion Disease Presenting with Diarrhea and Autonomic Neuropathy. New England Journal of Medicine , 369 (20) 1904- 1914. 10.1056/NEJMoa1214747. Green open access
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Mensah, A; Mulligan, C; Linehan, J; Ruf, S; O'Doherty, A; Grygalewicz, B; Shipley, J; ... Nizetic, D; + view all (2007) An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model. BMC Developmental Biology , 7 , Article 131. 10.1186/1471-213X-7-131. Green open access
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Norsworthy, PJ; Thompson, AGB; Mok, TH; Guntoro, F; Dabin, LC; Nihat, A; Paterson, RW; ... Viré, EA; + view all (2020) A blood miRNA signature associates with sporadic Creutzfeldt-Jakob disease diagnosis. Nature Communications , 11 (1) , Article 3960. 10.1038/s41467-020-17655-x. Green open access
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Purro, SA; Farrow, MA; Linehan, J; Nazari, T; Thomas, DX; Chen, Z; Mengel, D; ... Collinge, J; + view all (2018) Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone. Nature , 564 (7736) pp. 415-419. 10.1038/s41586-018-0790-y. Green open access
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Rayner, MLD; Day, AGE; Bhangra, KS; Sinden, J; Phillips, JB; (2021) Engineered neural tissue made using clinical-grade human neural stem cells supports regeneration in a long gap peripheral nerve injury model. Acta Biomaterialia , 135 pp. 203-213. 10.1016/j.actbio.2021.08.030. Green open access
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Rayner, MLD; Healy, J; Phillips, JB; (2021) Repurposing small molecules to target ppar-γ as new therapies for peripheral nerve injuries. Biomolecules , 11 (9) , Article 1301. 10.3390/biom11091301. Green open access
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Rayner, MLD; Brown, HL; Wilcox, M; Phillips, JB; Quick, TJ; (2020) Quantifying regeneration in patients following peripheral nerve injury. Journal of Plastic, Reconstructive & Aesthetic Surgery , 73 (2) pp. 201-208. 10.1016/j.bjps.2019.10.007. Green open access
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Rayner, MLD; Grillo, A; Williams, G; Tawfik, E; Zhang, T; Volitaki, C; Craig, DQM; ... Phillips, J; + view all (2020) Controlled local release of PPARγ agonists from biomaterials to treat peripheral nerve injury. Journal of Neural Engineering 10.1088/1741-2552/aba7cc. (In press). Green open access
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Rayner, MLD; Laranjeira, S; Evans, RE; Shipley, RJ; Healy, J; Phillips, JB; (2018) Developing an In Vitro Model to Screen Drugs for Nerve Regeneration. Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology , 301 (10) pp. 1628-1637. 10.1002/ar.23918. Green open access
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Reilly, Madeleine; Benilova, Iryna; Khalili-Shirazi, Azadeh; Schmidt, Christian; Ahmed, Parvin; Yip, Daniel; Jat, Parmjit S; (2022) A high-content neuron imaging assay demonstrates inhibition of prion disease-associated neurotoxicity by an anti-prion protein antibody. Scientific Reports , 12 , Article 9493. 10.1038/s41598-022-13455-z. Green open access
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Sandberg, MK; Al-Doujaily, H; Sharps, B; De Oliveira, MW; Schmidt, C; Richard-Londt, A; Lyall, S; ... Collinge, J; + view all (2014) Prion neuropathology follows the accumulation of alternate prion protein isoforms after infective titre has peaked. Nat Commun , 5 , Article 4347. 10.1038/ncomms5347. Green open access
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Schmidt, C; Fizet, J; Properzi, F; Batchelor, M; Sandberg, MK; Edgeworth, JA; Afran, L; ... Collinge, J; + view all (2015) A systematic investigation of production of synthetic prions from recombinant prion protein. Open Biology , 5 (12) , Article 150165. 10.1098/rsob.150165. Green open access
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Tattum, MH; Jones, S; Pal, S; Khalili-Shirazi, A; Collinge, J; Jackson, GS; (2010) A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K. Transfusion , 50 (12) 2619 - 2627. 10.1111/j.1537-2995.2010.02731.x. Green open access
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Trevitt, CR; Hosszu, LL; Batchelor, M; Panico, S; Terry, C; Nicoll, AJ; Risse, E; ... Clarke, AR; + view all (2014) N-terminal domain of prion protein directs its oligomeric association. J Biol Chem , 289 (37) 25497 - 25508. 10.1074/jbc.M114.566588. Green open access
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Wadsworth, JDF; Adamson, G; Joiner, S; Brock, L; Powell, C; Linehan, JM; Beck, JA; ... Collinge, J; + view all (2017) Methods for Molecular Diagnosis of Human Prion Disease. Methods in Molecular Biology: Prions , 1658 pp. 311-346. 10.1007/978-1-4939-7244-9_22. Green open access
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Wenborn, A; Terry, C; Gros, N; Joiner, S; D'Castro, L; Panico, S; Sells, J; ... Wadsworth, JD; + view all (2015) A novel and rapid method for obtaining high titre intact prion strains from mammalian brain. Scientific Reports , 5 , Article 10062. 10.1038/srep10062. Green open access
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Conference item

Rayner, M; Healy, J; Phillips, J; (2017) Investigating the effects of ibuprofen on axonal regeneration and functional recovery following peripheral nerve injury. Presented at: 6th Vienna Symposium on Surgery of Peripheral Nerves, Vienna, Austria.

Thesis

Rayner, Melissa Lucy Doreen; (2019) Investigating small molecule therapeutics to improve regeneration and functional recovery following peripheral nerve damage. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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This list was generated on Fri Oct 3 00:22:31 2025 BST.