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Number of items: 21.
Article
Bafadhel, M;
Barnes, N;
Bourke, SC;
Compton, C;
Criner, GJ;
Dransfield, MT;
Halpin, DMG;
... Singh, D; + view all
(2021)
A single blood eosinophil count measurement is as good as two for prediction of ICS treatment response in the IMPACT trial.
European Respiratory Journal
, 58
(3)
, Article 2004522. 10.1183/13993003.04522-2020.
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Bourdin, A;
Criner, G;
Devouassoux, G;
Dransfield, M;
Halpin, DMG;
Han, MK;
Jones, CE;
... Hanania, NA; + view all
(2021)
InforMing the PAthway of COPD Treatment (IMPACT Trial) Single-Inhaler Triple Therapy (Fluticasone Furoate/Umeclidinium/Vilanterol) Versus Fluticasone Furoate/Vilanterol and Umeclidinium/Vilanterol in Patients With COPD: Analysis o the Western Europe and North America Regions.
Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation
, 8
(1)
pp. 76-90.
10.15326/jcopdf.2020.0158.
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Celli, B;
Locantore, N;
Yates, JC;
Bakke, P;
Calverley, PMA;
Crim, C;
Coxson, HO;
... Evaluation of COPD Longitudinally to Identify Predictive Surroga; + view all
(2021)
Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort.
European Respiratory Journal
, 57
(3)
, Article 2001339. 10.1183/13993003.01339-2020.
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Engleitner, H;
Jha, A;
Herron, D;
Nelson, A;
Rees, G;
McNally, N;
Williams, B;
(2021)
Enrolment in clinical research at UCLH and geographically distributed indices of deprivation [version 1; peer review: awaiting peer review].
Wellcome Open Research
, 6
, Article 342. 10.12688/wellcomeopenres.17300.1.
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Fromme, M;
Schneider, CV;
Pereira, V;
Hamesch, K;
Pons, M;
Reichert, MC;
Benini, F;
... Strnad, P; + view all
(2021)
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency.
Gut
10.1136/gutjnl-2020-323729.
(In press).
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Gordon, C;
Yardley, S;
Lomas, DA;
Edwards, SJL;
(2021)
Limitations to Contingency Measures: Reflections from COVID-19 Surges in the UK.
The American Journal of Bioethics
, 21
(8)
pp. 31-34.
10.1080/15265161.2021.1940365.
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Han, MK;
Criner, GJ;
Dransfield, MT;
Halpin, DMG;
Jones, CE;
Kilbride, S;
Lange, P;
... Singh, D; + view all
(2021)
Prognostic value of clinically important deterioration in COPD: IMPACT trial analysis.
ERJ Open Research
, 7
(1)
, Article 00663-2020. 10.1183/23120541.00663-2020.
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Hanania, NA;
Mannino, DM;
Criner, GJ;
Dransfield, MT;
Han, MK;
Jones, CE;
Kilbride, S;
... Lipson, DA; + view all
(2021)
Effect of Age on the Efficacy and Safety of Once-Daily Single-Inhaler Triple Therapy Fluticasone Furoate/Umeclidinium/Vilanterol in Patients With Chronic Obstructive Pulmonary Disease: A Post Hoc Analysis of the IMPACT Trial.
Chest
, 159
(3)
pp. 985-995.
10.1016/j.chest.2020.09.253.
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Lakshman Kumar, P;
Wilson, AC;
Rocco, A;
Cho, MH;
Wan, E;
Hobbs, BD;
Washko, GR;
... McDonald, MLN; + view all
(2021)
Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary disease.
Journal of Cachexia, Sarcopenia and Muscle
10.1002/jcsm.12782.
(In press).
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Liddle, J;
Pearce, AC;
Arico-Muendel, C;
Belyanskaya, S;
Brewster, A;
Brown, M;
Chung, C-W;
... Lomas, DA; + view all
(2021)
The development of highly potent and selective small molecule correctors of Z α1-antitrypsin misfolding.
Bioorganic & Medicinal Chemistry Letters
, 41
, Article 127973. 10.1016/j.bmcl.2021.127973.
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Lomas, DA;
Irving, JA;
Arico-Muendel, C;
Belyanskaya, S;
Brewster, A;
Brown, M;
Chung, C-W;
... Pearce, AC; + view all
(2021)
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin.
EMBO Molecular Medicine
, Article e13167. 10.15252/emmm.202013167.
(In press).
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McKimpson, WM;
Chen, Y;
Irving, JA;
Zheng, M;
Weinberger, J;
Tan, WLW;
Tiang, Z;
... Kitsis, RN; + view all
(2021)
Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes.
Developmental Cell
, 56
(6)
747-760.e6.
10.1016/j.devcel.2021.02.011.
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Olszewska, DA;
Fearon, C;
McGuigan, C;
McVeigh, TP;
Houlden, H;
Polke, JM;
Lawlor, B;
... Lynch, T; + view all
(2021)
A clinical, molecular genetics and pathological study of a FTDP-17 family with a heterozygous splicing variant c.823-10G>T at the intron 9/exon 10 of the MAPT gene.
Neurobiology of Aging
, 106
343.e1-343.e8.
10.1016/j.neurobiolaging.2021.05.010.
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Raccosta, S;
Librizzi, F;
Jagger, AM;
Noto, R;
Martorana, V;
Lomas, DA;
Irving, JA;
(2021)
Scaling Concepts in Serpin Polymer Physics.
Materials
, 14
(10)
, Article 2577. 10.3390/ma14102577.
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Ronzoni, R;
Ferrarotti, I;
D’Acunto, E;
Balderacchi, AM;
Ottaviani, S;
Lomas, DA;
Irving, JA;
... Fra, A; + view all
(2021)
The Importance of N186 in the Alpha-1-Antitrypsin Shutter Region Is Revealed by the Novel Bologna Deficiency Variant.
International Journal of Molecular Sciences
, 22
(11)
, Article 5668. 10.3390/ijms22115668.
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Shipley, RJ;
Brealey, D;
Haniffa, R;
Elwell, C;
Baker, T;
Lomas, DA;
Singer, M;
(2021)
Lessons and risks of medical device deployment in a global pandemic.
The Lancet Global Health
10.1016/S2214-109X(21)00028-0.
(In press).
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Singh, D;
Criner, GJ;
Dransfield, MT;
Halpin, DMG;
Han, MLK;
Lange, P;
Lettis, S;
... Lomas, D; + view all
(2021)
InforMing the PAthway of COPD Treatment (IMPACT) trial: fibrinogen levels predict risk of moderate or severe exacerbations.
Respiratory Research
, 22
(1)
10.1186/s12931-021-01706-y.
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Smith, M;
Abdesselem, HB;
Mullins, M;
Tan, T-M;
Nel, AJM;
Al-Nesf, MAY;
Bensmail, I;
... Blackburn, JM; + view all
(2021)
Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort.
Viruses
, 13
(5)
, Article 786. 10.3390/v13050786.
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Turner, CT;
Brown, J;
Shaw, E;
Uddin, I;
Tsaliki, E;
Roe, JK;
Pollara, G;
... Noursadeghi, M; + view all
(2021)
Persistent T Cell Repertoire Perturbation and T Cell Activation in HIV After Long Term Treatment.
Frontiers Immunology
, 12
, Article 634489. 10.3389/fimmu.2021.634489.
(In press).
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Vass, L;
Fisk, M;
Cheriyan, J;
Mohan, D;
Forman, J;
Oseni, A;
Devaraj, A;
... Wilkinson, IB; + view all
(2021)
Quantitative 18F-fluorodeoxyglucose positron emission tomography/computed tomography to assess pulmonary inflammation in COPD.
ERJ Open Research
, 7
(3)
, Article 00699-2020. 10.1183/23120541.00699-2020.
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Yu, R;
Hanley, B;
Denegri, S;
Ahmed, J;
McNally, NJ;
(2021)
Evaluation of a patient and public involvement training programme for researchers at a large biomedical research centre in the UK.
BMJ Open
, 11
(8)
, Article e047995. 10.1136/bmjopen-2020-047995.
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