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The development of contraceptive vaccines

Delves, PJ; (2002) The development of contraceptive vaccines. EXPERT OPIN INV DRUG , 11 (9) 1225 - 1237. Green open access

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Abstract

The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning. However, only this one Phase II trial has been completed despite a plethora of hormonal and gamete antigens that have been proposed as candidate vaccines. Improvements in the design and formulation of contraceptive vaccines are underway and will be a necessary prelude to further clinical trials.

Type: Article
Title: The development of contraceptive vaccines
Open access status: An open access version is available from UCL Discovery
Keywords: antifertility, contraception, glycoprotein hormones, oocyte, spermatozoa, vaccine, HUMAN CHORIONIC-GONADOTROPIN, B-CELL EPITOPE, RIBOFLAVIN CARRIER PROTEIN, PELLUCIDA GLYCOPROTEIN-B, BIRTH-CONTROL VACCINE, MOUSE ZONA-PELLUCIDA, SPERM-EGG BINDING, MALE GUINEA-PIGS, BETA-SUBUNIT, ANTIFERTILITY VACCINES
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity
URI: https://discovery.ucl.ac.uk/id/eprint/917
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