Delves, PJ;
(2002)
The development of contraceptive vaccines.
EXPERT OPIN INV DRUG
, 11
(9)
1225 - 1237.
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Abstract
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning. However, only this one Phase II trial has been completed despite a plethora of hormonal and gamete antigens that have been proposed as candidate vaccines. Improvements in the design and formulation of contraceptive vaccines are underway and will be a necessary prelude to further clinical trials.
Type: | Article |
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Title: | The development of contraceptive vaccines |
Open access status: | An open access version is available from UCL Discovery |
Keywords: | antifertility, contraception, glycoprotein hormones, oocyte, spermatozoa, vaccine, HUMAN CHORIONIC-GONADOTROPIN, B-CELL EPITOPE, RIBOFLAVIN CARRIER PROTEIN, PELLUCIDA GLYCOPROTEIN-B, BIRTH-CONTROL VACCINE, MOUSE ZONA-PELLUCIDA, SPERM-EGG BINDING, MALE GUINEA-PIGS, BETA-SUBUNIT, ANTIFERTILITY VACCINES |
UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Infection and Immunity |
URI: | https://discovery.ucl.ac.uk/id/eprint/917 |
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