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Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis

Paun, S; Lund, VJ; Gallimore, A; (2005) Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis. Journal of Laryngology and Otology , 119 (2) 119 - 124. 10.1258/0022215053419989. Green open access

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Abstract

Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis. We describe four cases of the disease centred around the nasal cavity, with widespread infiltration of the facial soft tissues and orbit in three of the four patients. Each underwent long term follow up. Multiple surgical resections were required with two of our patients and, to date, medical therapy has been of limited help. The disease process, with its clinical and characteristic histopathological findings, is described. We also discuss the management of the disease following a comprehensive review of, and comparison with, the few prior reported cases.

Type: Article
Title: Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis
Open access status: An open access version is available from UCL Discovery
DOI: 10.1258/0022215053419989
Publisher version: http://dx.doi.org/10.1258/0022215053419989
Language: English
Additional information: Copyright Cambridge University Press 2004
Keywords: Eosinophilic Angiocentric Fibrosis, Upper Respiratory Tract, Nasal Septum, Stenosis
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute
URI: https://discovery.ucl.ac.uk/id/eprint/619
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