UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Understanding premenstrual syndrome

Fry, J; Honour, J; (1998) Understanding premenstrual syndrome. The Lancet , 351 (9114) 1511 - 1511. 10.1016/S0140-6736(05)78900-5.

[thumbnail of Fry_%26 Honour 1998.pdf] Text
Fry_%26 Honour 1998.pdf
Access restricted to UCL open access staff

Download (46kB)

Abstract

In her Feb 14 commentary, Sarah Berga rightly draws attention to the possible importance of progesterone and its neuroactive metabolites for our understanding of the premenstrual syndrome. She discusses the report of A J Rapkin and colleagues, who found serum concentrations of the progesterone metabolite allopreg-nanolone during the luteal phase to be lower in women with premenstrual syndrome than in symptom-free women. However, her explanation of the importance of this finding in terms of alternative pathways of progesterone metabolism to neuroactive compounds with different effects on the central nervous system (CNS) is incorrect and was never claimed by the original investigators.

Type: Article
Title: Understanding premenstrual syndrome
DOI: 10.1016/S0140-6736(05)78900-5
Publisher version: http://dx.doi.org/10.1016/S0140-6736(05)78900-5
Language: English
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Neuro, Physiology and Pharmacology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
URI: https://discovery.ucl.ac.uk/id/eprint/22071
Downloads since deposit
1Download
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item