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Imaging in extrapulmonary tuberculosis

Gambhir, S; Ravina, M; Rangan, K; Dixit, M; Barai, S; Bomanji, J; International Atomic Energy Agency Extra-pulmonary TB Consortium, .; (2016) Imaging in extrapulmonary tuberculosis. International Journal of Infectious Diseases , 56 pp. 237-247. 10.1016/j.ijid.2016.11.003. Green open access

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Abstract

Tuberculosis (TB) remains a major global public health problem, with 1.5 million deaths annually worldwide. One in five cases of TB present as extrapulmonary TB (EPTB), posing major diagnostic and management challenges. Mycobacterium tuberculosis adapts to a quiescent physiological state and is notable for its complex interaction with the host, producing poorly understood disease states ranging from latent infection to active clinical disease. New tools in the diagnostic armamentarium are urgently required for the rapid diagnosis of TB and monitoring of TB treatments, and to gain new insights into pathogenesis. The typical and atypical imaging features of EPTB are reviewed herein, and the roles of several imaging modalities for the diagnosis and management of EPTB are discussed.

Type: Article
Title: Imaging in extrapulmonary tuberculosis
Location: Canada
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.ijid.2016.11.003
Publisher version: http://dx.doi.org/10.1016/j.ijid.2016.11.003
Language: English
Additional information: 2016 Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: (18)F-fluorodeoxyglucose (FDG) PET–CT, Biomarker, CT, Extrapulmonary tuberculosis, Imaging, MRI, PET–CT, Tuberculosis
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1537538
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