UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

The chemistry of ynol and thioynol ethers

Wilden, JD; Gray, VJ; (2016) The chemistry of ynol and thioynol ethers. Organic and Biomolecular Chemistry , 14 (41) pp. 9695-9711. 10.1039/C6OB01776B. Green open access

[thumbnail of wilden_Thioynol Ether Synthesis Accepted.pdf]
Preview
Text
wilden_Thioynol Ether Synthesis Accepted.pdf

Download (3MB) | Preview

Abstract

Alkynyl ethers and alkynyl thioethers (‘ynol ethers’ and ‘thioynol ethers’) are appealing building-blocks in synthetic chemistry due to their ease of manipulation and predictable reactivity. Until recently however, their potential has remained underexploited due to difficulties in preparation and isolation. Although recent advances in synthetic chemistry have highlighted various applications for ynol ethers, the equivalent thioynol examples have been rather less exploited despite a unique and fascinating reactivity profile. Although superficially the chemistry of alkynyl ethers and their sulfide counterparts are similar, close examination of their chemistry reveals important differences which can be exploited by the synthetic chemist. This review will examine the preparation of both classes of compound and examine their reactivity to highlight their powerful synthetic applications. Particular focus will be made of thiynol ethers whose chemistry exhibits some fascinating differences compared to their oxygen counterparts and have immense untapped potential for synthetic chemistry.

Type: Article
Title: The chemistry of ynol and thioynol ethers
Open access status: An open access version is available from UCL Discovery
DOI: 10.1039/C6OB01776B
Publisher version: http://dx.doi.org/10.1039/C6OB01776B
Language: English
Additional information: © The Royal Society of Chemistry 2016
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Chemistry
URI: https://discovery.ucl.ac.uk/id/eprint/1519700
Downloads since deposit
338Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item