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Early and long-term outcome of infants born extremely preterm

Johnson, S; Marlow, N; (2016) Early and long-term outcome of infants born extremely preterm. Archives of Disease in Childhood , 102 (1) pp. 97-102. 10.1136/archdischild-2015-309581. Green open access

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Abstract

There is no question that birth at extremely low gestational ages presents a significant threat to an infant's survival, health and development. Growing evidence suggests that gestational age may be conceptualised as a continuum in which births before 28 weeks of gestation (extremely preterm: EP) represent the severe end of a spectrum of health and developmental adversity. Although comprising just 1%–2% of all births, EP deliveries pose the greatest challenge to neonatal medicine and to health, education and social services for the provision of ongoing support for survivors with additional needs. Studying the outcomes of these infants remains critical for evaluating and enhancing clinical care, planning long-term support and for advancing our understanding of the life-course consequences of immaturity at birth. Here we review literature relating to early and long-term neurodevelopmental, cognitive, behavioural and educational outcomes following EP birth focusing on key themes and considering implications for intervention.

Type: Article
Title: Early and long-term outcome of infants born extremely preterm
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/archdischild-2015-309581
Publisher version: http://doi.org/10.1136/archdischild-2015-309581
Language: English
Additional information: Copyright © 2017 The Author(s). Published by the BMJ Publishing Group Limited. All rights reserved. This article has been accepted for publication in Archives of Disease in Childhood following peer review. The definitive copyedited, typeset version Johnson, S; Marlow, N; (2016) Early and long-term outcome of infants born extremely preterm. Archives of Disease in Childhood , 102 (1) pp. 97-102 is available online at: http://doi.org/10.1136/archdischild-2015-309581
Keywords: Science & Technology, Life Sciences & Biomedicine, Pediatrics, Low-birth-weight, School-aged Children, Mental-health, Executive Function, Adolescents Born, Gestational-age, Follow-up, Neurobehavioral Outcomes, Regional Differences, Functional Outcomes
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > UCL EGA Institute for Womens Health > Neonatology
URI: https://discovery.ucl.ac.uk/id/eprint/1508675
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