UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Using functional imaging to understand therapeutic effects in poststroke aphasia

Crinion, JT; Leff, AP; (2015) Using functional imaging to understand therapeutic effects in poststroke aphasia. Current Opinion in Neurology , 28 (4) pp. 330-337. 10.1097/WCO.0000000000000217. Green open access

[thumbnail of Crinion_using_functional_imaging_to_understand.pdf]
Preview
Text
Crinion_using_functional_imaging_to_understand.pdf

Download (472kB) | Preview

Abstract

PURPOSE OF REVIEW: The evidence base for the treatment of poststroke aphasia continues to grow, so too does interest in the neural mechanisms that underlie these therapy-driven improvements. Although the majority of patients respond to therapy, not all of those who do improve do so in a predictable way. Here, we review 17 of the most recent articles that have attempted to deal with this important question, dividing them into those that target speech perception and production. RECENT FINDINGS: There are many methodological differences between the studies, but some neuroimaging patterns have emerged: whether the in-scanner language task is speech perception or production, left hemisphere fronto-temporal cortex is often activated/correlated with language improvement and; right inferior frontal gyrus is frequently identified although what this represents is still hotly contested. We are concerned that many studies are not well controlled making it difficult to ascribe neuroimaging changes directly to the therapeutic intervention. SUMMARY: Encouragingly, there are many more functional imaging studies in this challenging area of research. Behaviour, either alone or paired with structural imaging data, only goes part way in explaining aphasic patients’ responses to therapy. An important emerging theme is exploring the role that nonlanguage cognitive processes play in aphasia recovery.

Type: Article
Title: Using functional imaging to understand therapeutic effects in poststroke aphasia
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/WCO.0000000000000217
Publisher version: http://dx.doi.org/ 10.1097/WCO.0000000000000217
Language: English
Additional information: Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.
Keywords: Language Therapy, Stroke, Reorganization, Connectivity, Recovery, Speech, Sleep, Motor
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Div of Psychology and Lang Sciences > Institute of Cognitive Neuroscience
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery.ucl.ac.uk/id/eprint/1477681
Downloads since deposit
385Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item