UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Patient-specific computational models to support interventional procedures: a case study of complex aortic re-coarctation

Cosentino, D; Capelli, C; Derrick, G; Khambadkone, S; Muthurangu, V; Taylor, AM; Schievano, S; (2015) Patient-specific computational models to support interventional procedures: a case study of complex aortic re-coarctation. EuroIntervention , 11 (6) pp. 669-672. 10.4244/EIJY15M09_03.

[img] Text
Capelli_Patient-specificComputationalModelsToSupportInterventionalProcedures_ACaseStudyOfComplexAorticReCoarctation.pdf
Access restricted to UCL open access staff

Download (2MB)

Abstract

AIMS: We report the application of patient-specific computational models to plan the treatment of complex aortic re-coarctation (rCoA) with a proximal aberrant right subclavian artery in a patient who had previously undergone bare metal stenting. METHODS AND RESULTS: Clinically acquired images were used to set up patient-specific computational models for finite element (FE) and fluid dynamics (CFD) analyses. The 3D geometry was reconstructed from computed tomography and echocardiography images. Computer-generated deployment of a CP covered stent (NuMED, Hopkinton, NY, USA) at different diameters was tested using FE simulations. CFD analyses based on preoperative magnetic resonance flow measurements allowed assessment of rCoA pressure relief and right subclavian artery perfusion in the different scenarios. The simulations suggested an expansion diameter for the CP stent (8 zigs, length=28 mm) of between 16 and 18 mm to relieve the obstruction, cover the aneurysm and maintain satisfactory flow to the right subclavian artery. Following the modelling study, a 16 mm CP covered stent was successfully implanted. CONCLUSIONS: Patient-specific models can be successfully used to plan re-stenting of complex rCoA, showing the benefits of integrating computational techniques into patient management.

Type: Article
Title: Patient-specific computational models to support interventional procedures: a case study of complex aortic re-coarctation
DOI: 10.4244/EIJY15M09_03
Publisher version: http://dx.doi.org/10.4244/EIJY15M09_03
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Computational fluid dynamics, coarctation of the aorta, finite element, patient-specific modelling
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Cardiovascular Science > Children's Cardiovascular Disease
URI: https://discovery.ucl.ac.uk/id/eprint/1477663
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item