Lazzarino, AI;
Hamer, M;
Carvalho, L;
Gaze, D;
Collinson, P;
Steptoe, A;
(2015)
The mediation of coronary calcification in the association between risk scores and cardiac troponin T elevation in healthy adults: Is atherosclerosis a good prognostic precursor of coronary disease?
Preventive Medicine
, 77
pp. 150-154.
10.1016/j.ypmed.2015.05.025.
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Abstract
Conventional cardiac risk scores may not be completely accurate in predicting acute events because they only include factors associated with atherosclerosis, considered as the fundamental precursor of cardiovascular disease. In UK in 2006-2008 (Whitehall II study) we tested the ability of several risk scores to identify individuals with cardiac cell damage and assessed to what extent their estimates were mediated by the presence of atherosclerosis.
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