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Laboratory-based X-ray phase-contrast imaging with misaligned optical elements

Endrizzi, M; Basta, D; Olivo, A; (2015) Laboratory-based X-ray phase-contrast imaging with misaligned optical elements. [Letter]. Applied Physics Letters , 107 (12) , Article 124103. 10.1063/1.4931778. Green open access

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Abstract

We report on a laboratory X-ray phase-contrast imaging technique based on the edge illumination principle that substantially relaxes the existing limitations on system set up and data acquisition, allowing an increase in tolerance of misalignments by at least two orders of magnitude. The robustness of this approach was systematically studied by means of experiments with our prototype. Numerical simulations were also performed in order to assess the dependence of the image quality on the data acquisition scheme. The results show that errors in the positioning of the masks within a 1 degree range for all the angles, and within 1 mm range of translation, do not noticeably affect image quality. We also show that, if the misalignment does not exceed few tens of micrometers, three intensity projections are sufficient to effectively retrieve the three representations of the sample, allowing for optimization of dose or time efficiency even with a non-ideal system.

Type: Article
Title: Laboratory-based X-ray phase-contrast imaging with misaligned optical elements
Location: USA
Open access status: An open access version is available from UCL Discovery
DOI: 10.1063/1.4931778
Publisher version: http://dx.doi.org/10.1063/1.4931778
Language: English
Additional information: © 2015 AIP Publishing LLC. All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in 'Laboratory-based X-ray phase-contrast imaging with misaligned optical elements Endrizzi, Marco and Basta, Dario and Olivo, Alessandro, Applied Physics Letters, 107, 124103 (2015), DOI:http://dx.doi.org/10.1063/1.4931778' and may be found at http://dx.doi.org/10.1063/1.4931778.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/1471171
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