Singer, M;
(2013)
Biomarkers in sepsis.
Curr Opin Pulm Med
, 19
(3)
305 - 309.
10.1097/MCP.0b013e32835f1b49.
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Abstract
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely revolutionize the management of sepsis. These markers will facilitate early and accurate diagnosis, faster recognition of impending organ dysfunction, optimal selection and titration of appropriate therapies, and more reliable prognostication of risk and outcome. These diagnostics will also enable an improved characterization of the biological phenotype underlying sepsis and thus a better appreciation of the condition. Summary: The potential for novel biomarkers in sepsis will need to be properly realized with considerable funding, academic–industry collaborations, appropriate investigations and validation in heterogenous populations, but these developments do hold the capacity to transform patient care and outcomes.
| Type: | Article |
|---|---|
| Title: | Biomarkers in sepsis. |
| Location: | United States |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1097/MCP.0b013e32835f1b49 |
| Publisher version: | http://dx.doi.org/10.1097/MCP.0b013e32835f1b49 |
| Language: | English |
| Additional information: | Copyright: © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins. This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Biological Markers, Early Diagnosis, Humans, Multiple Organ Failure, Predictive Value of Tests, Prognosis, Risk, Sensitivity and Specificity, Sepsis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Experimental and Translational Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1466629 |
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