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The clinical use of nuclear magnetic resonance spectroscopy for studying human muscle metabolism.

Cady, EB; Griffiths, RD; Edwards, RHT; (1985) The clinical use of nuclear magnetic resonance spectroscopy for studying human muscle metabolism. International Journal of Technology Assessment in Health Care , 1 (3) 631 - 645. 10.1017/S0266462300001537. Green open access

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Abstract

Nuclear magnetic resonance (NMR) imaging has recently become an accepted technique in the medical practitioner's armory (38). NMR spectroscopy (44) is a subtly different application of the same physical principles underlying NMR imaging, but the clinical potential for this modality is currently still under evaluation. The most important application of clinical NMR spectroscopy is for the nonin-vasive monitoring of changes in metabolite levels and intracellular pH of intact tissues during physiological stress or in response to pharmacological agents or disease. The 31phosphorus (31P) nucleus has been the most commonly investigated in muscle disease (39) but the applications of proton (1H), (4,5,8) and 13carbon (13C), (2,7) are currently being explored.

Type: Article
Title: The clinical use of nuclear magnetic resonance spectroscopy for studying human muscle metabolism.
Open access status: An open access version is available from UCL Discovery
DOI: 10.1017/S0266462300001537
Publisher version: http://dx.doi.org/10.1017/S0266462300001537
Language: English
Additional information: © 1985 Cambridge University Press
Keywords: NMR, MRS, phosphorus, 31P, muscle, metabolism
UCL classification: UCL
UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
URI: https://discovery.ucl.ac.uk/id/eprint/145618
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