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Electrolyte disorders

Bockenhauer, D; Zieg, J; (2014) Electrolyte disorders. Clinics in Perinatology , 41 (3) pp. 575-590. 10.1016/j.clp.2014.05.007. Green open access

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Abstract

Electrolyte disorders can result in life-threatening complications. The kidneys are tasked with maintaining electrolyte homoeostasis, yet the low glomerular filtration rate of neonatal kidneys, tubular immaturity, and high extrarenal fluid losses contribute to increased occurrence of electrolyte disorders in neonates. Understanding the physiologic basis of renal electrolyte handling is crucial in identifying underlying causes and initiation of proper treatment. This article reviews key aspects of renal physiology, the diagnostic workup of disorders of plasma sodium and potassium, and the appropriate treatment, in addition to inherited disorders associated with neonatal electrolyte disturbances that illuminate the physiology of renal electrolyte handling.

Type: Article
Title: Electrolyte disorders
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.clp.2014.05.007
Publisher version: http://dx.doi.org/10.1016/j.clp.2014.05.007
Language: English
Additional information: © 2014. This manuscript version is published under a Creative Commons Attribution Non-commercial Non-derivative 4.0 International licence (CC BY-NC-ND 4.0). This licence allows you to share, copy, distribute and transmit the work for personal and non-commercial use providing author and publisher attribution is clearly stated. Further details about CC BY licences are available at http://creativecommons.org/licenses/by/4.0.
Keywords: Electrolyte disorders, Hyperkalemia, Hypernatremia, Hypokalemia, Hyponatremia, Newborn, Renal physiology, Glomerular Filtration Rate, Humans, Infant, Newborn, Kidney, Kidney Diseases, Water-Electrolyte Imbalance
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Renal Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/1447308
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