UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Timing Precision in Population Coding of Natural Scenes in the Early Visual System

Desbordes, G; Jin, JZ; Weng, C; Lesica, NA; Stanley, GB; Alonso, JM; (2008) Timing Precision in Population Coding of Natural Scenes in the Early Visual System. PLoS Biology , 6 (12) , Article e324. 10.1371/journal.pbio.0060324. Green open access

[thumbnail of 141010.pdf]
Preview
PDF
141010.pdf

Download (579kB)

Abstract

The timing of spiking activity across neurons is a fundamental aspect of the neural population code. Individual neurons in the retina, thalamus, and cortex can have very precise and repeatable responses but exhibit degraded temporal precision in response to suboptimal stimuli. To investigate the functional implications for neural populations in natural conditions, we recorded in vivo the simultaneous responses, to movies of natural scenes, of multiple thalamic neurons likely converging to a common neuronal target in primary visual cortex. We show that the response of individual neurons is less precise at lower contrast, but that spike timing precision across neurons is relatively insensitive to global changes in visual contrast. Overall, spike timing precision within and across cells is on the order of 10 ms. Since closely timed spikes are more efficient in inducing a spike in downstream cortical neurons, and since fine temporal precision is necessary to represent the more slowly varying natural environment, we argue that preserving relative spike timing at a similar to 10-ms resolution is a crucial property of the neural code entering cortex.

Type: Article
Title: Timing Precision in Population Coding of Natural Scenes in the Early Visual System
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pbio.0060324
Publisher version: http://dx.doi.org/10.1371/journal.pbio.0060324
Language: English
Additional information: © 2008 Desbordes et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords: LATERAL GENICULATE-NUCLEUS, NEURONAL SPIKE TRAINS, RECEPTIVE-FIELD PROPERTIES, STOCHASTIC POINT PROCESSES, RETINAL GANGLION-CELLS, RESPONSE VARIABILITY, CORTICAL-NEURONS, NEURAL CODE, CORTEX, INFORMATION
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > The Ear Institute
URI: https://discovery.ucl.ac.uk/id/eprint/141010
Downloads since deposit
91Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item