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Role of insulin-like growth factor binding protein-4 in prevention of colon cancer

Durai, R; Yang, SY; Seifalian, AM; Goldspink, G; Winslet, MC; (2007) Role of insulin-like growth factor binding protein-4 in prevention of colon cancer. World Journal of Surgical Oncology , 5 , Article 128. 10.1186/1477-7819-5-128. Green open access

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Abstract

Insulin-like growth factors (IGFs) are important for the proliferation of cancer cells. One of their binding proteins, known as insulin-like growth factor binding protein -4 (IGFBP-4) is well known for its inhibitory action on IGFs in vitro. We assessed the effect of IGFBP-4 in prevention of development of colon cancer in vivo.

Type: Article
Title: Role of insulin-like growth factor binding protein-4 in prevention of colon cancer
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1186/1477-7819-5-128
Publisher version: http://dx.doi.org/10.1186/1477-7819-5-128
Language: English
Additional information: PMCID: PMC2203999 © 2007 Durai et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Clinical and Movement Neurosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/139939
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