Wright, KE;
Liniker, E;
MacRobert, AJ;
Brown, RA;
Saffrey, MJ;
Phillips, JB;
(2006)
Investigating the effect of photodynamic therapy on nerves using tissue engineered culture models.
In:
Abstracts of the Tissue and Cell Engineering Society (TCES) meeting 3-4 July 2006, University of Sheffield.
(pp. 51 - 51).
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Abstract
Photodynamic therapy (PDT) shows potential as an effective treatment for prostate cancer. Clinical observations indicate that this approach causes fewer nerve damage related side effects than conventional treatments. The aim here is to investigate the effect of PDT on nerve tissue using engineered 3-dimensional cell culture models. Initial experiments focussed on establishing photosensitiser localisation in neurones and Schwann cells, then developing a model for simulating nerve PDT in culture.
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