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Mechanical behaviour of primary human skeletal muscle cells and isolated non-myogenic cells within a 3D- construct

Brady, M; Brown, R; Lewis, M; Mudera, V; (2005) Mechanical behaviour of primary human skeletal muscle cells and isolated non-myogenic cells within a 3D- construct. In: Abstracts of TCES (Tissue and Cell Engineering Society) meeting 2005 May 20-22, 2005 - Queen Mary, University of London. (pp. 29 - 29). Green open access

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Abstract

INTRODUCTION: An understanding of the mechanical and mechano-molecular responses that occur during the differentiation of primary human myoblasts in 3D-culture is critical for understanding growth and progress towards producing a tissue-engineered muscle construct1. In an effort to characterise the mechanical behaviour of myoblasts within a 3D construct, previous work by Cheema et al. (2003) utilised a cell line of immortalised skeletal myoblasts (c2c12 cells). The aim of this study was to determine the mechanical response of primary human skeletal muscle (PHSM) cells. Further, to isolate myoblasts from PHSM cells and establish the force generated by those cells.

Type: Proceedings paper
Title: Mechanical behaviour of primary human skeletal muscle cells and isolated non-myogenic cells within a 3D- construct
Event: TCES (Tissue and Cell Engineering Society) meeting
Location: Queen Mary, University of London
Dates: 20 May 2005- 22 May 2005
Open access status: An open access version is available from UCL Discovery
Publisher version: http://www.ecmjournal.org/journal/supplements/vol0...
Language: English
Additional information: Reproduced with kind permission from eCM journal (www.ecmjournal.org)
Keywords: Ortho, Cells, Human, July, Muscle, Other, Skeletal muscle
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
URI: https://discovery.ucl.ac.uk/id/eprint/1348460
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