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Robust and fast whole brain mapping of the RF transmit field B1 at 7T.

Lutti, A; Stadler, J; Josephs, O; Windischberger, C; Speck, O; Bernarding, J; Hutton, C; (2012) Robust and fast whole brain mapping of the RF transmit field B1 at 7T. PLoS One , 7 (3) , Article e32379. 10.1371/journal.pone.0032379. Green open access

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Abstract

In-vivo whole brain mapping of the radio frequency transmit field B(1) (+) is a key aspect of recent method developments in ultra high field MRI. We present an optimized method for fast and robust in-vivo whole-brain B(1) (+) mapping at 7T. The method is based on the acquisition of stimulated and spin echo 3D EPI images and was originally developed at 3T. We further optimized the method for use at 7T. Our optimization significantly improved the robustness of the method against large B(1) (+) deviations and off-resonance effects present at 7T. The mean accuracy and precision of the optimized method across the brain was high with a bias less than 2.6 percent unit (p.u.) and random error less than 0.7 p.u. respectively.

Type: Article
Title: Robust and fast whole brain mapping of the RF transmit field B1 at 7T.
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1371/journal.pone.0032379
Publisher version: http://dx.doi.org/10.1371/journal.pone.0032379
Language: English
Additional information: © 2012 Lutti et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. PMCID: PMC3299646 This study was financially supported by the Wellcome Trust (http://www.wellcome.ac.uk/, grant number 079866/Z/06/Z), the BMBF (German Federal Ministry of Education and Research, project number 13N9208) and the MAN-BIOPSY research cluster of the Medical University of Vienna and the University of Vienna, Austria (SO76300004). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Keywords: Brain Mapping, Computer Simulation, Germany, Humans, Imaging, Three-Dimensional, Magnetic Fields, Magnetic Resonance Imaging, Models, Theoretical, Whole Body Imaging
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Imaging Neuroscience
URI: https://discovery.ucl.ac.uk/id/eprint/1346183
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