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Potential of Novel EPO Derivatives in Limb Ischemia

Joshi, D; Tsui, J; Yu, R; Shiwen, X; Selvakumar, S; Abraham, DJ; Baker, DM; (2012) Potential of Novel EPO Derivatives in Limb Ischemia. Cardiology Research and Practice , 2012 , Article 213785. 10.1155/2012/213785. Green open access

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Abstract

Erythropoietin (EPO) has tissue-protective properties, but it increases the risk of thromboembolism by raising the haemoglobin concentration. New generation of EPO derivatives is tissue protective without the haematopoietic side effects. Preclinical studies have demonstrated their effectiveness and safety. This paper summarizes the development in EPO derivatives with emphasis on their potential use in critical limb ischaemia.

Type: Article
Title: Potential of Novel EPO Derivatives in Limb Ischemia
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1155/2012/213785
Publisher version: http://dx.doi.org/10.1155/2012/213785
Language: English
Additional information: © 2012 Dhiraj Joshi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. PMCID: PMC3296231
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
URI: https://discovery.ucl.ac.uk/id/eprint/1345815
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