Neild, GH;
Rodriguez-Justo, M;
Wall, C;
Connolly, JO;
(2006)
Hyper-IgG4 disease: report and characterisation of a new disease.
BMC Medicine
, 4
, Article 23. 10.1186/1741-7015-4-23.
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Abstract
We highlight a chronic inflammatory disease we call 'hyper-IgG4 disease', which has many synonyms depending on the organ involved, the country of origin and the year of the report. It is characterized histologically by a lymphoplasmacytic inflammation with IgG4-positive cells and exuberant fibrosis, which leaves dense fibrosis on resolution. A typical example is idiopathic retroperitoneal fibrosis, but the initial report in 2001 was of sclerosing pancreatitis.
| Type: | Article |
|---|---|
| Title: | Hyper-IgG4 disease: report and characterisation of a new disease |
| Location: | England |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1186/1741-7015-4-23 |
| Publisher version: | http://dx.doi.org/10.1186/1741-7015-4-23 |
| Language: | English |
| Additional information: | PMCID: PMC1618394 © 2006 Neild et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons. org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the orig inal work is properly cited. |
| Keywords: | Adult, Diagnosis, Differential, Diagnostic Errors, Humans, Hypergammaglobulinemia, Immunoglobulin G, Male, Plasma Cells, Retroperitoneal Fibrosis |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Pathology UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1307283 |
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