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The role of thalamic group II mGlu receptors in health and disease

Copeland, CS; Salt, TE; (2022) The role of thalamic group II mGlu receptors in health and disease. Neuronal Signaling , 6 (4) , Article NS20210058. 10.1042/NS20210058. Green open access

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Abstract

The thalamus plays a pivotal role in the integration and processing of sensory, motor, and cognitive information. It is therefore important to understand how the thalamus operates in states of both health and disease. In the present review, we discuss the function of the Group II metabotropic glutamate (mGlu) receptors within thalamic circuitry, and how they may represent therapeutic targets in treating disease states associated with thalamic dysfunction.

Type: Article
Title: The role of thalamic group II mGlu receptors in health and disease
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1042/NS20210058
Publisher version: https://doi.org/10.1042/NS20210058
Language: English
Additional information: Copyright © 2022 The Author(s). This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) (http://creativecommons.org/licenses/by/4.0/). Open access for the present article was enabled by the participation of University College London in an all-inclusive Read & Publish agreement with Portland Press and the Biochemical Society under a transformative agreement with JISC.
Keywords: astrocytes, glutamate receptor, synapses, thalamus
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10186462
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