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Time varying association between deprivation, ethnicity and SARS-CoV-2 infections in England: A population-based ecological study

Padellini, T; Jersakova, R; Diggle, PJ; Holmes, C; King, RE; Lehmann, BCL; Mallon, AM; ... Blangiardo, M; + view all (2022) Time varying association between deprivation, ethnicity and SARS-CoV-2 infections in England: A population-based ecological study. The Lancet Regional Health - Europe , 15 , Article 100322. 10.1016/j.lanepe.2022.100322. Green open access

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Abstract

BACKGROUND: Ethnically diverse and socio-economically deprived communities have been differentially affected by the COVID-19 pandemic in the UK. METHOD: Ethnically diverse and socio-economically deprived communities have been differentially affected by the COVID-19 pandemic in the UK. FINDINGS: Comparing the least deprived and predominantly White areas with most deprived and predominantly non-White areas over the whole study period, the weekly positivity rate increases from 2·977% (95% CrI 2.913%-3.029%) to 3·347% (95% CrI 3.300%-3.402%). Similarly, prevalence increases from 0·369% (95% CrI 0.361%-0.375%) to 0·405% (95% CrI 0.399%-0.412%). Deprivation has a stronger effect until October 2020, while the effect of ethnicity becomes more pronounced at the peak of the second wave and then again in May-June 2021. In the second wave of the pandemic, LTLAs with large South Asian populations were the most affected, whereas areas with large Black populations did not show increased values for either outcome during the entire period under analysis. INTERPRETATION: Deprivation and proportion of non-White populations are both associated with an increased COVID-19 burden in terms of disease spread and monitoring, but the strength of association varies over the course of the pandemic and for different ethnic subgroups. The consistency of results across the two outcomes suggests that deprivation and ethnicity have a differential impact on disease exposure or susceptibility rather than testing access and habits. FUNDINGS: EPSRC, MRC, The Alan Turing Institute, NIH, UKHSA, DHSC.

Type: Article
Title: Time varying association between deprivation, ethnicity and SARS-CoV-2 infections in England: A population-based ecological study
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.lanepe.2022.100322
Publisher version: https://doi.org/10.1016/j.lanepe.2022.100322
Language: English
Additional information: © 2022 The Authors. Published by Elsevier Ltd. under a Creative Commons license (http://creativecommons.org/licenses/by/4.0/).
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Statistical Science
URI: https://discovery.ucl.ac.uk/id/eprint/10184175
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