Lepri, Gemma;
Hughes, Michael;
Allanore, Yannick;
Denton, Christopher P;
Furst, Daniel E;
Wang, Yukai;
Santiago, Tania;
... Matucci-Cerinic, Marco; + view all
(2023)
The role of skin ultrasound in systemic sclerosis: looking below the surface to understand disease evolution.
The Lancet Rheumatology
, 5
(7)
e422-e425.
10.1016/S2665-9913(23)00100-5.
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Abstract
Skin ultrasound has shown promising results in the evaluation of skin involvement in patients with systemic sclerosis, as substantiated by a recent systematic literature review from the World Scleroderma Foundation Skin Ultrasound Working Group. In this Viewpoint, we will discuss the role of ultrasound in evaluating skin involvement in patients with systemic sclerosis, particularly the possibility of using this technique to detect an early subclinical skin involvement from the very early phase, suggesting its possible use in both diagnosis and disease follow-up. To detect subclinical skin involvement, it is essential to understand the difference between the skin of patients with systemic sclerosis and that of healthy controls, including defining exactly which structures are affected by the disease and which are spared. The potential of this non-invasive technique might suggest its future role in both clinical practice and clinical trials, possibly replacing invasive and painful procedures such as skin biopsies and promoting patient retention in clinical trials.
| Type: | Article |
|---|---|
| Title: | The role of skin ultrasound in systemic sclerosis: looking below the surface to understand disease evolution |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/S2665-9913(23)00100-5 |
| Publisher version: | https://doi.org/10.1016/S2665-9913(23)00100-5 |
| Language: | English |
| Additional information: | This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions. |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10173278 |
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