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Realistic expectations are key to realising the benefits of polygenic scores

Sud, A; Horton, RH; Hingorani, AD; Tzoulaki, I; Turnbull, C; Houlston, RS; Lucassen, A; (2023) Realistic expectations are key to realising the benefits of polygenic scores. BMJ , 380 , Article e073149. 10.1136/bmj-2022-073149. Green open access

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Abstract

We must not let enthusiasm around polygenic scores allow us to forget other factors that are bigger, more modifiable, and relevant for everyone, argue Amit Sud, Rachel Horton, and colleagues

Type: Article
Title: Realistic expectations are key to realising the benefits of polygenic scores
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1136/bmj-2022-073149
Publisher version: https://doi.org/10.1136/bmj-2022-073149
Language: English
Additional information: This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Keywords: Humans, Multifactorial Inheritance, Disease, Risk
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
URI: https://discovery.ucl.ac.uk/id/eprint/10172553
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