Grafton-Clarke, Ciaran;
Thornton, George;
Fidock, Benjamin;
Archer, Gareth;
Hose, Rod;
van der Geest, Rob J;
Zhong, Liang;
... Garg, Pankaj; + view all
(2023)
Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions [version 3; peer review: 1 approved, 1 approved with reservations].
Wellcome Open Research
, 6
, Article 253. 10.12688/wellcomeopenres.17200.3.
Preview |
Text
ffec803a-a73b-461d-a55b-d629c016552a_17200_-_ciaran_grafton-clarke_v3.pdf - Published Version Download (1MB) | Preview |
Abstract
BACKGROUND: The reproducibility of mitral regurgitation (MR) quantification by cardiovascular magnetic resonance (CMR) imaging using different software solutions remains unclear. This research aimed to investigate the reproducibility of MR quantification between two software solutions: MASS (version 2019 EXP, LUMC, Netherlands) and CAAS (version 5.2, Pie Medical Imaging). METHODS: CMR data of 35 patients with MR (12 primary MR, 13 mitral valve repair/replacement, and ten secondary MR) was used. Four methods of MR volume quantification were studied, including two 4D-flow CMR methods (MRMVAV and MRJet) and two non-4D-flow techniques (MRStandard and MRLVRV). We conducted within-software and inter-software correlation and agreement analyses. RESULTS: All methods demonstrated significant correlation between the two software solutions: MRStandard (r=0.92, p<0.001), MRLVRV (r=0.95, p<0.001), MRJet (r=0.86, p<0.001), and MRMVAV (r=0.91, p<0.001). Between CAAS and MASS, MRJet and MRMVAV, compared to each of the four methods, were the only methods not to be associated with significant bias. CONCLUSIONS: We conclude that 4D-flow CMR methods demonstrate equivalent reproducibility to non-4D-flow methods but greater levels of agreement between software solutions.
| Type: | Article |
|---|---|
| Title: | Mitral regurgitation quantification by cardiac magnetic resonance imaging (MRI) remains reproducible between software solutions [version 3; peer review: 1 approved, 1 approved with reservations] |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.12688/wellcomeopenres.17200.3 |
| Publisher version: | http://doi.org/10.12688/wellcomeopenres.17200.3 |
| Language: | English |
| Additional information: | © 2023 Grafton-Clarke C et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Keywords: | Magnetic resonance imaging; Mitral valve insufficiency; Reproducibility of results |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10170164 |
Archive Staff Only
 |
View Item |
