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Cardiovascular Magnetic Resonance Imaging in Familial Dilated Cardiomyopathy

Lau, C; Gul, U; Liu, B; Captur, G; Hothi, SS; (2023) Cardiovascular Magnetic Resonance Imaging in Familial Dilated Cardiomyopathy. Medicina , 59 (3) , Article 439. 10.3390/medicina59030439. Green open access

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Abstract

Dilated cardiomyopathy (DCM) is a common cause of non-ischaemic heart failure, conferring high morbidity and mortality, including sudden cardiac death due to systolic dysfunction or arrhythmic sudden death. Within the DCM cohort exists a group of patients with familial disease. In this article we review the pathophysiology and cardiac imaging findings of familial DCM, with specific attention to known disease subtypes. The role of advanced cardiac imaging cardiovascular magnetic resonance is still accumulating, and there remains much to be elucidated. We discuss its potential clinical roles as currently known, with respect to diagnostic utility and risk stratification. Advances in such risk stratification may help target pharmacological and device therapies to those at highest risk.

Type: Article
Title: Cardiovascular Magnetic Resonance Imaging in Familial Dilated Cardiomyopathy
Location: Switzerland
Open access status: An open access version is available from UCL Discovery
DOI: 10.3390/medicina59030439
Publisher version: https://doi.org/10.3390/medicina59030439
Language: English
Additional information: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Keywords: CMR, DCM, cardiovascular magnetic resonance imaging, familial dilated cardiomyopathy, Humans, Cardiomyopathy, Dilated, Magnetic Resonance Imaging, Death, Sudden, Cardiac, Heart Failure
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine > MRC Unit for Lifelong Hlth and Ageing
URI: https://discovery.ucl.ac.uk/id/eprint/10168338
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