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Roadmap for precision preclinical x-ray radiation studies

Verhaegen, Frank; Butterworth, Karl T; Chalmers, Anthony J; Coppes, Rob P; de Ruysscher, Dirk; Dobiasch, Sophie; Fenwick, John D; ... Dubois, Ludwig J; + view all (2023) Roadmap for precision preclinical x-ray radiation studies. Physics in Medicine & Biology , 68 (6) , Article 06RM01. 10.1088/1361-6560/acaf45. Green open access

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Abstract

This Roadmap paper covers the field of precision preclinical x-ray radiation studies in animal models. It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technological evolution in imaging, irradiation, dosimetry and monitoring that have empowered these kinds of studies is discussed, and many developments in the near future are outlined. Finally, clinical translation and reverse translation are discussed.

Type: Article
Title: Roadmap for precision preclinical x-ray radiation studies
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1088/1361-6560/acaf45
Publisher version: https://doi.org/10.1088/1361-6560%2Facaf45
Language: English
Additional information: © 2023 IOP Publishing. Original content from this work may be used under the terms of the Creative Commons Attribution 4.0 licence (http://creativecommons.org/licenses/by/4.0).
Keywords: cancer models, dosimetry, imaging, irradiation, precision, preclinical, translation, Animals, X-Rays, Radiometry, Radiography, Models, Animal, Phantoms, Imaging
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10168326
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