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The importance of long-lived proteins: Not just nuclear anymore

Erinjeri, Annmary Paul; Labbadia, John; (2021) The importance of long-lived proteins: Not just nuclear anymore. Developmental Cell , 56 (21) pp. 2925-2927. 10.1016/j.devcel.2021.10.015. Green open access

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Abstract

The significance of mitochondrial long-lived proteins (mitoLLPs) to tissue health has remained mysterious for over a decade. In this issue of Developmental Cell, Krishna et al. demonstrate that mitochondrial lifetimes are highly heterogeneous and that mitoLLPs promote respiratory capacity by facilitating supercomplex assembly within the electron transport chain.

Type: Article
Title: The importance of long-lived proteins: Not just nuclear anymore
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.devcel.2021.10.015
Publisher version: https://doi.org/10.1016/j.devcel.2021.10.015
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: https://discovery.ucl.ac.uk/id/eprint/10160884
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