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Developing a framework for CBCT-to-CT synthesis in paediatric abdominal radiotherapy

Szmul, Adam; Taylor, Sabrina; Lim, Pei; Cantwell, Jessica; D'Souza, Derek; Moinuddin, Syed; Gaze, Mark; ... Correia Veloso Da Veiga, Catarina Isabel; + view all (2021) Developing a framework for CBCT-to-CT synthesis in paediatric abdominal radiotherapy. In: Proceedings of the 25th UK Conference on Medical Image Understanding and Analysis. (pp. pp. 1-4). : Medical Image Understanding and Analysis (MIUA). Green open access

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Abstract

We proposed a CBCT-to-CT synthesis framework tailored for paediatric abdominal patients. Our approach was based on the cycle-consistent generative adversarial network (cycleGAN) modified to preserve structural consistency. To adjust for differences in field-of-view and body size from different patient groups, our training data was spatially co-registered to a common field-of-view and normalised to a fixed size. The proposed framework showed improvements in generating synthetic CTs from CBCTs compared to the original implementation of cycleGAN without field-of-view adjustments and structural consistency constrain.

Type: Proceedings paper
Title: Developing a framework for CBCT-to-CT synthesis in paediatric abdominal radiotherapy
Event: The 25th UK Conference on Medical Image Understanding and Analysis
Open access status: An open access version is available from UCL Discovery
Publisher version: https://miua2021.com/abstracts/119.pdf
Language: English
Additional information: This version is the version of record. For information on re-use, please refer to the publisher's terms and conditions.
Keywords: Cone-beam computed tomography (CBCT), computer tomography (CT), cycle-consistent generative adversarial networks (cycleGANs), synthetic images, childhood cancer, abdominal neuroblastoma, paediatric radiotherapy
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10159129
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