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Personalized external aortic root support in aneurysm disease

Treasure, Tom; Austin, Conal; Kenny, Louise Amelia; Pepper, John; (2022) Personalized external aortic root support in aneurysm disease. Current Opinion in Cardiology , 37 (6) pp. 454-458. 10.1097/HCO.0000000000000990. Green open access

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Abstract

PURPOSE OF REVIEW: To bring together and annotate publications about personalised external aortic reported in the 18 months preceding submission. RECENT FINDINGS: The total number of personalised external aortic root support (PEARS) operations is now approaching 700 in 32 centres in Australia, Belgium, Brazil, Czech Republic, Great Britain, Greece, Ireland, Malaysia, Netherlands, New Zealand, Poland and Slovakia. There are continued reports of stability of aortic dimensions and aortic valve function with the only exceptions known being where the surgeon has deviated from the directions for use of the device. The median root diameter of Marfan patients having PEARS was 47 mm suggesting that the existing criterion of 50 mm is due for reconsideration. The peri-operative mortality in the first 200 patients was 0.5% and is currently estimated to be less than 0.2%. The first recipient remains alive and well after 18 years. The use of PEARS as an adjunct to the Ross operation to support the pulmonary autograft is being explored in several centres. SUMMARY: The operation requires proctoring and adherence to a strict operative protocol and with those precautions excellent results are attained. The evidence and opinions provided in these publications indicate that this is proven and successful prophylactic operation for aortic root aneurysm.

Type: Article
Title: Personalized external aortic root support in aneurysm disease
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1097/HCO.0000000000000990
Publisher version: https://doi.org/10.1097/HCO.0000000000000990
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher's terms and conditions.
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics > Clinical Operational Research Unit
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > Dept of Mathematics
URI: https://discovery.ucl.ac.uk/id/eprint/10155983
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