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Investigating the use of Mechanochemistry to Improve the Sustainability of Chemical Synthesis and Drug Discovery

Payne, Riley; (2022) Investigating the use of Mechanochemistry to Improve the Sustainability of Chemical Synthesis and Drug Discovery. Masters thesis (M.Phil), UCL (University College London). Green open access

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Abstract

Presented herein is an exploration into mechanochemical techniques for organic synthesis. Mechanochemistry is an exciting tool where mechanical energy is used to enable reactivity via the impact of balls within a jar. It has recently gained increased interest due to the unique solvent free reaction set-up. Currently, from a sustainability perspective, organic synthesis can be an incredibly wasteful endeavour that must be improved to ensure more sustainable working practices. In this report, three distinctive areas have been targeted to either uncover a new process or improve on reactions that are frequently used in the chemical industry.

Type: Thesis (Masters)
Qualification: M.Phil
Title: Investigating the use of Mechanochemistry to Improve the Sustainability of Chemical Synthesis and Drug Discovery
Open access status: An open access version is available from UCL Discovery
Language: English
Additional information: Copyright © The Author 2021. Original content in this thesis is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) Licence (https://creativecommons.org/licenses/by-nc/4.0/). Any third-party copyright material present remains the property of its respective owner(s) and is licensed under its existing terms. Access may initially be restricted at the author’s request. - Some third party copyright material has been removed from this e-thesis.
UCL classification: UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10151833
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