Bass, Cher;
Silva, Mariana da;
Sudre, Carole H;
Williams, Logan ZJ;
Tudosiu, Petru-Daniel;
Alfaro-Almagro, Fidel;
Fitzgibbon, Sean P;
... Robinson, Emma C; + view all
(2021)
ICAM-reg: Interpretable Classification and Regression with Feature Attribution for Mapping Neurological Phenotypes in Individual Scans.
In:
Medical Imaging with Deep Learning – MIDL 2021.
: Lübeck, Germany.
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Abstract
Feature attribution (FA), or the assignment of class-relevance to different locations in an image, is important for many classification and regression problems but is particularly crucial within the neuroscience domain, where accurate mechanistic models of behaviours, or disease, require knowledge of all features discriminative of a trait. At the same time, predicting class relevance from brain images is challenging as phenotypes are typically heterogeneous, and changes occur against a background of significant natural variation. Here, we present an extension of the ICAM framework for creating prediction specific FA maps through image-to-image translation.
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