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Robustness to misalignment of low-cost, compact quantitative phase imaging architectures

Fitzpatrick, Catherine RM; Wilson, Abby; Sawyer, Travis W; Christopher, Peter J; Wilkinson, Timothy D; Bohndiek, Sarah E; Gordon, George SD; (2020) Robustness to misalignment of low-cost, compact quantitative phase imaging architectures. OSA Continuum , 3 (10) pp. 2660-2679. 10.1364/osac.395498. Green open access

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Abstract

Non-interferometric approaches to quantitative phase imaging could enable its application in low-cost, miniaturised settings such as capsule endoscopy. We present two possible architectures and both analyse and mitigate the effect of sensor misalignment on phase imaging performance. This is a crucial step towards determining the feasibility of implementing phase imaging in a capsule device. First, we investigate a design based on a folded 4f correlator, both in simulation and experimentally. We demonstrate a novel technique for identifying and compensating for axial misalignment and explore the limits of the approach. Next, we explore the implications of axial and transverse misalignment, and of manufacturing variations on the performance of a phase plate-based architecture, identifying a clear trade-off between phase plate resolution and algorithm convergence time. We conclude that while the phase plate architecture is more robust to misalignment, both architectures merit further development with the goal of realising a low-cost, compact system for applying phase imaging in capsule endoscopy.

Type: Article
Title: Robustness to misalignment of low-cost, compact quantitative phase imaging architectures
Open access status: An open access version is available from UCL Discovery
DOI: 10.1364/osac.395498
Publisher version: https://doi.org/10.1364/OSAC.395498
Language: English
Additional information: © 2022 Optica Publishing Group. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/).
UCL classification: UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Mechanical Engineering
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL
URI: https://discovery.ucl.ac.uk/id/eprint/10146901
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